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CASP16 — LRRC59

Text-mined interactions from Literome

Yu et al., Cancer Res 2002 (MAP Kinase Signaling System) : Synergistic potentiation of STI571 mediated lethality by PD184352 was associated with multiple perturbations in signaling and apoptotic regulatory pathways, including caspase dependent down-regulation of Bcr-Abl and Bcl-2 ; caspase independent down-regulation of Bcl-x ( L ) and Mcl-1 ; activation of JNK, p38 MAPK, and p34 ( cdc2 ) ; and diminished phosphorylation of Stat5 and CREB
Koeppel et al., J Biol Chem 2004 : PS-GAP interacts specifically with caspase activated PAK-2p34 , but not active or inactive full-length PAK-2, through a region between the GAP and SH3 domains