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MAPK10 — SRY
Text-mined interactions from Literome
Bogani et al., PLoS Biol 2009
(Disorders of Sex Development...) :
Moreover, we describe experiments showing the presence of activated MKK4, a direct target of MAP3K4, and activated p38 in the coelomic region of the XY gonad at 11.5 d post coitum, establishing a link between
MAPK signalling in proliferating gonadal somatic cells and
regulation of
Sry expression
Gierl et al., Dev Cell 2012
(Gonadal Dysgenesis, 46,XY...) :
Moreover, the transcription factor GATA4, which is required for Sry expression, binds to the
Sry promoter in vivo in a
MAPK dependent manner