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MAPK10 — SOCS1
Text-mined interactions from Literome
Jegalian et al., J Interferon Cytokine Res 2002
:
Using two independent approaches, one involving inhibition of specific signaling molecules and the other employing cell lines that express particular EpoR mutants and thereby activate only subsets of signaling cascades, we demonstrate that induction of
SOCS1 , SOCS2, SOCS3, and cytokine-inducible SH2 containing protein ( CIS ) in response to EPO stimulation appears to
depend on Stat5 but not on
mitogen activated protein kinase ( MAPK ) or phosphatidylinositol 3-kinase (PI3K)
Park et al., Biochem Biophys Res Commun 2007
(Breast Neoplasms) :
Finally, inhibition of p38
MAPK activity
blocked the induction of
SOCS1 expression by NDRG2, resulting in the recovery of STAT3 phosphorylation level