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MAPK10 — SLCO6A1
Text-mined interactions from Literome
Mischiati et al., AIDS 1999
(MAP Kinase Signaling System) :
Moreover, both GST-Tat2E and
GST-Tat1E also
stimulated ERK/MAPK
Grant et al., Plant J 2000
:
In contrast, studies using a panel of protein kinase and phosphatase inhibitors and in-gel kinase assays in these mutant backgrounds suggested that a 48 kDa
mitogen activated protein kinase ( MAPK ) activity was
required for the activation of
gst1 and pal1 in response to redox cues
Shih et al., Biochemistry 2001
(MAP Kinase Signaling System) :
T ( 4 ) also caused nuclear co-immunoprecipitation of TRbeta1 and p53, an effect also inhibited by PD. Nuclear complexing of p53 and MAPK also occurred in HeLa cells, which lack functional TR. Constitutively activated
MAPK caused phosphorylation of a recombinant
p53-GST fusion protein in vitro ; thus, p53 is a substrate for MAPK
Seitz et al., J Clin Immunol 2003
(MAP Kinase Signaling System) :
In contrast,
GST did not
affect cytokine mRNA expression or
MAPK activation
Yacoub et al., Mol Cancer Ther 2008
(Glioblastoma) :
In GBM6 cells,
GST-MDA-7 ( 30 nmol/L ) transiently
activated p38
mitogen activated protein kinase , which was modestly protective against JNK1-3 induced toxicity, whereas GST-MDA-7 ( 300 nmol/L ) caused prolonged intense p38 mitogen activated protein kinase activation, which promoted cell death
Lim et al., Environ Toxicol Chem 2012
:
The results also suggest that
GST and HIF-1 activation by AgNP exposure are PMK-1 p38
MAPK dependent , and that both play an important role in the PMK-1 p38 MAPK mediated defense pathway to AgNP exposure in C. elegans
Komatsu et al., Arch Biochem Biophys 1997
:
The protein kinase activity of
GST-MAPKAPK-4 was
activated by
MAPK and this enabled the kinase to phosphorylate both glycogen synthase N-terminal peptide and the regulatory light chain of myosin II in vitro