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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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MAP3K5 — MAPK10

Text-mined interactions from Literome

Korchnak et al., Cell Signal 2009 : Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase ( MAP3K ) that activates multiple mitogen activated protein kinase ( MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
Wu et al., Free Radic Biol Med 2010 (Drug-Induced Liver Injury) : These studies show that TNFalpha increases oxidative stress in mice with elevated CYP2E1, with subsequent activation of ASK-1 via a mechanism involving thioredoxin-ASK-1 dissociation, followed by activation of downstream MKK and MAPK