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ECM1 — MAPK10
Text-mined interactions from Literome
Gooch et al., J Biol Chem 2001
(Hypertrophy) :
Inhibition of either
MAPK or PI3K, however,
had no effect on IGF-I induced hypertrophy or
ECM production
Khan et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
Here we demonstrate that macrophage engagement of
SMC-ECM triggers PKC dependent activation of
MAPK ( erk1/2 ) leading to increased expression of cyclooxygenase (COX)-2 and prostaglandin ( PG ) E ( 2 ) synthesis
Ha et al., Life Sci 2006
:
Inhibitor of ERK or p38
MAPK suppressed PDGF induced MC proliferation and
ECM synthesis ... In conclusion, MPA inhibits p38 MAPK activation leading to inhibiting proliferation and
ECM synthesis in MC. Guanosine reduction is partially
responsible for inhibitory effect of MPA on p38
MAPK activation in MC
Hamamura et al., Cell Biol Int 2010
:
ECM dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK and p38
MAPK of osteoblast-like cells