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CX3CR1 — MAPK10
Text-mined interactions from Literome
Lee et al., Eur J Pain 2010
:
Interleukin-6
induces microglial
CX3CR1 expression in the spinal cord after peripheral nerve injury through the activation of p38
MAPK ... These results suggest a new mechanism of neuropathic pain, in which IL-6
induces microglial
CX3CR1 expression in the spinal cord through p38
MAPK activation, enhancing the responsiveness of microglia to fractalkine in the spinal cord, thus playing an important role in neuropathic pain after peripheral nerve injury
Gan et al., Cell Tissue Res 2013
(Inflammation) :
Inhibitors of
p38MAPK , JAK-STAT, NF-kB, and AP-1 significantly
reduced CX3CL1 and
CX3CR1 expression