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CREB5 — IGF2

Text-mined interactions from Literome

Liu et al., Endocrinology 2002 : Consistent with the effect of IGF-I on CREB phosphorylation, IGF-I increased the transcriptional activity of CREB , although it had no effect on CREB binding to DNA
Moorehead et al., Oncogene 2003 (Adenocarcinoma, Bronchiolo-Alveolar...) : Moreover, IGF-II induced proliferation and CREB phosphorylation in human lung cancer cell lines, suggesting that IGF-II and CREB also contribute to the growth of human lung tumors ... Moreover, IGF-II induced proliferation and CREB phosphorylation in human lung cancer cell lines, suggesting that IGF-II and CREB also contribute to the growth of human lung tumors
Linnerth et al., Oncogene 2005 (Adenocarcinoma, Bronchiolo-Alveolar...) : IGF-II induces CREB phosphorylation and cell survival in human lung cancer cells ... Further, the effects of IGF-II on cell survival and CREB phosphorylation appeared to be mediated, at least in part, by activation of the Erk pathways, as inhibition of these signaling pathways reduced tumor cell survival and CREB phosphorylation ... Therefore, our results indicate that CREB and its associated proteins play a significant role in lung adenocarcinoma and IGF-II induces CREB phosphorylation, at least in part, via the Erk5 signaling pathway
Maldonado et al., Biochem Biophys Res Commun 2005 (Calcium Signaling) : In cultured cardiac myocytes, IGF-1 induced phosphorylation ( 6.5 +/- 1.0-fold at 5 min ), nuclear translocation ( 30 min post-stimulus ) and DNA binding activity of CREB
Genua et al., Cancer Res 2009 (Prostatic Neoplasms) : In conclusion, we describe a novel mechanism of IGF-IR up-regulation and promoter activity by CREB activation, induced by sex steroids, through a nongenotropic signaling
Yan et al., Dev Neurobiol 2013 : Additionally, IGF-I stimulated CREB phosphorylation was blunted by the MAP kinase inhibitor, PD98059, but not by the PI3 kinase inhibitor, wortmannin