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BSG — MAPK1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Tang et al., Mol Cancer Res 2006
(Breast Neoplasms...) :
Conversely, inhibition of
EMMPRIN expression
resulted in suppressed Akt and
MAPK phosphorylation
Qian et al., J Exp Clin Cancer Res 2008
(Carcinoma, Hepatocellular...) :
Western blot assay was utilized to detect the
effects of
si-CD147 on focal adhesion kinase ( FAK ), vinculiln and
mitogen activated protein kinase ( MAPK ) expression in SMMC-7721 cells
Fan et al., Int J Cardiol 2011
(Acute Coronary Syndrome...) :
By using the p38 inhibitor and NF-?B inhibitor, the study established that
EMMPRIN and MMP-9 inductions by iron deficiency
required the consecutive upstream activation of p38
MAPK and NF-?B
Fan et al., Int J Mol Med 2011
(Plaque, Atherosclerotic) :
Exogenous nicotinamide mononucleotide ( NMN ), the product of nicotinamide phosphoribosyltransferase ( NAMPT ) activity, mimicked the effects of visfatin on
MAPK ( p38, ERK1/2 ) -NF-?B activation and
EMMPRIN/MMP-9 induction
Dai et al., Int J Cancer 2012
:
We found that KSHV activation of
emmprin induces PI3K/Akt- and
mitogen activated protein kinase ( MAPK ) -dependent secretion of vascular endothelial growth factor ( VEGF ) ... Functionally, EC invasion following de novo infection is induced by
emmprin dependent PI3K/Akt and
MAPK activation of VEGF