◀ Back to IFNG
IFNG — RBBP4
Text-mined interactions from Literome
Osborne et al., Mol Cell Biol 2001
:
These findings represent the first evidence that
HDAC activity can
repress IFN-gamma-inducible HLA class II gene expression and also demonstrate that HDAC activity can contribute to promoter repression following the establishment of a DNase I-hypersensitive chromatin conformation
Guo et al., Mol Cells 2006
:
Our data indicate that
IFNgamma and STAT dependent gene transcription
requires the participation of
HDAC , as does the IFNalpha-STAT pathway
Keslacy et al., Mol Pharmacol 2007
(Inflammation) :
It is noteworthy that
IFNgamma decreases TNFalpha induced histone acetyl transferase ( HAT ) and
increases histone deacetylase (HDAC) activities
Choi et al., J Immunol 2009
:
Importantly,
histone deacetylase (HDAC) inhibitors significantly
enhanced IFN-gamma-inducible gene expression in trophoblast cells, but not fibroblasts ... We propose that
HDAC mediated inhibition of
IFN-gamma-inducible gene expression in mouse trophoblast cells may contribute to successful pregnancy by preventing activation of IFN-gamma responses that might otherwise facilitate the destruction of the placenta
Brown et al., J Interferon Cytokine Res 1997
:
The
NRD ( NF-kappa B/Rel/Dorsal ) complexes
induced by LPS and
IFN-gamma were further characterized by addition of antisera to electrophoretic mobility shift assay ( EMSA ) reaction mixtures