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IFNG — NEUROD1
Text-mined interactions from Literome
Wong et al., Exp Neurol 2004
:
Interferon-gamma but not TNF alpha
promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells ... Under differentiating conditions, neither cytokine was toxic ; however,
IFN gamma enhanced
neuronal differentiation , rapidly increasing beta III-tubulin positive cell numbers 3-4 fold and inhibiting astrocyte generation
Song et al., J Biol Chem 2005
:
Here we studied the underlying mechanism for
IFN-gamma induced
neuronal differentiation using the human neuroblastoma Paju cell line
Zahir et al., Stem Cells Dev 2009
:
These in vitro screens showed that of all the different treatments, dibutyryl cyclic AMP ( dbcAMP ) and
interferon-gamma (IFN-gamma) enhanced
neuronal differentiation most significantly compared to the 1 % fetal bovine serum ( FBS ) controls
Arien-Zakay et al., Leukemia 2009
(Neuroblastoma) :
Interferon-gamma induced
neuronal differentiation of human umbilical cord blood derived progenitors ... These data indicate that
IFN-gamma promotes
neuronal differentiation of HUCB derived progenitors, proposing its use in future protocols towards cell therapy