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NOS1 — PDB1
Text-mined interactions from Literome
McKenna et al., Shock 1994
:
LPS and
beta-PDB induced a sustained translocation of PKC activity from the cytosol to the membrane, an increased protein synthesis dependent expression of
nitric oxide synthase (NOS) activity, and an impaired contractility that could be partially reversed by treatment with the NOS inhibitor N omega-nitro-L-arginine methyl ester ... Sphingosine blocked LPS- and
beta-PDB induced
NOS activity and LPS induced impairments in tissue contractility and PKC translocation
McKenna et al., Am J Physiol 1995
:
PKC blockade with sphingosine, chelerythrine, or calphostin-C precluded LPS- and
beta-PDB induced increases in
NOS activity and protected contractility