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CCL2 — TNFSF12

Text-mined interactions from Literome

Kawakita et al., Biochem Biophys Res Commun 2004 (Carcinoma, Hepatocellular...) : We found that TWEAK also promotes cell proliferation and induces the secretion of IL-8 and MCP-1 in human umbilical vein endothelial cell
Mueller et al., J Neuroimmunol 2005 (Chronic Disease...) : TWEAK increased the secretion of CCL2 [ monocyte chemotactic protein-1 (MCP-1) ] by CNS endothelial cells and astrocytes in vitro, suggesting CCL2 as a critical mediator of TWEAKs proinflammatory effects ... Purified IgG from TWEAK- or Fn14 vaccinated rats prevented TWEAK induced production of CCL2 by endothelial cells
Campbell et al., J Immunol 2006 : TWEAK stimulation of mesangial cells led to a dose dependent increase in CCL2/MCP-1 , CCL5/RANTES, CXCL10/IFN-gamma induced protein 10 kDa, and CXCL1/KC
Kang et al., Biochem Biophys Res Commun 2008 (Melanoma...) : Exogenous Tweak stimulated high level CCL2 production in siMAML transfected M624 cells, which was critically dependent on Tweak-TweakR ligation
Wako et al., Spine (Phila Pa 1976) 2008 : In addition, TWEAK also induced monocyte chemotactic protein (MCP)-1 via the NF-kappaB pathway, as phosphorylation of NF-kappaB was confirmed by western blotting ... TWEAK also induces MCP-1 , which belongs to the chemokine family that recruits inflammatory cells via the NF-kappaB pathway
Kumar et al., J Immunol 2009 (Inflammation) : TWEAK induced expression of proinflammatory genes such as MMP-9, CCL-2 , and VCAM-1 was also reduced in TAK1 ( -/- ) MEF compared with wild-type MEF
Muñoz-García et al., Arterioscler Thromb Vasc Biol 2009 (Atherosclerosis...) : Furthermore, ox-LDL and TWEAK synergized for induction of MCP-1 and RANTES expression and secretion
Haile et al., J Cereb Blood Flow Metab 2010 (Brain Ischemia) : Here, we show that TWEAK induces a dose dependent increase in the expression of the chemokine monocyte chemoattractant protein-1 ( MCP-1 ) in astrocytes, and that this effect is mediated by its interaction with Fn14 via nuclear factor-kappaB pathway activation
Abend et al., J Virol 2010 : Finally, the downregulation of TWEAKR by miR-K10a in primary human endothelial cells resulted in a decrease in levels of expression of the proinflammatory cytokines interleukin-8 (IL-8) and monocyte chemoattractant protein 1 ( MCP-1 ) in response to TWEAK
Moreno et al., Arterioscler Thromb Vasc Biol 2013 (Aortic Diseases...) : TWEAK also increased monocyte chemoattractant protein-1 secretion in human acute monocytic leukemia cell line cells, an effect blocked with an HMGB1 small interfering RNA
Ucero et al., PloS one 2013 (Disease Models, Animal...) : Tweak induced MCP-1 and Rantes synthesis through JAK2 kinase and NF-?B activation
Gu et al., PloS one 2013 (Carcinoma...) : Further, TWEAK increased monocyte chemoattractant protein-1 ( MCP-1 ) production in cultured HO-8910PM cells to possibly recruit macrophages