ID:WDR65_HUMAN DESCRIPTION: RecName: Full=WD repeat-containing protein 65; INDUCTION: May be an IRF6-target. DISEASE: Defects in WDR65 may be the cause of van der Woude syndrome type 2 (VWS2) [MIM:606713]. An autosomal dominant developmental disorder characterized by lower lip pits, cleft lip and/or cleft palate. SIMILARITY: Contains 10 WD repeats.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96MR6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.