Human Gene BLTP3B (ENST00000279907.12_13) from GENCODE V47lift37
  Description: UHRF1 binding protein 1 like, transcript variant 1 (from RefSeq NM_015054.2)
Gencode Transcript: ENST00000279907.12_13
Gencode Gene: ENSG00000111647.13_17
Transcript (Including UTRs)
   Position: hg19 chr12:100,430,850-100,536,652 Size: 105,803 Total Exon Count: 21 Strand: -
Coding Region
   Position: hg19 chr12:100,431,414-100,536,413 Size: 105,000 Coding Exon Count: 21 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:100,430,850-100,536,652)mRNA (may differ from genome)Protein (1464 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: UH1BL_HUMAN
DESCRIPTION: RecName: Full=UHRF1-binding protein 1-like;
SEQUENCE CAUTION: Sequence=AAI27018.1; Type=Frameshift; Positions=1004; Sequence=CAB66755.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.57 RPKM in Artery - Tibial
Total median expression: 217.56 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -107.00239-0.448 Picture PostScript Text
3' UTR -109.80564-0.195 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026728 - UHRF1BP1_like
IPR026854 - VPS13A_N

Pfam Domains:
PF12624 - N-terminal region of Chorein or VPS13

ModBase Predicted Comparative 3D Structure on A0JNW5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details Gene Details  
Gene SorterGene Sorter Gene Sorter  
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding
GO:0042803 protein homodimerization activity

Cellular Component:
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005829 cytosol
GO:0000938 GARP complex


-  Descriptions from all associated GenBank mRNAs
  BC127017 - Homo sapiens UHRF1 binding protein 1-like, mRNA (cDNA clone MGC:149898 IMAGE:40124660), complete cds.
AK125813 - Homo sapiens cDNA FLJ43825 fis, clone TESTI4002647.
BC014891 - Homo sapiens UHRF1 binding protein 1-like, mRNA (cDNA clone IMAGE:3908507), complete cds.
LF384684 - JP 2014500723-A/192187: Polycomb-Associated Non-Coding RNAs.
KJ906079 - Synthetic construct Homo sapiens clone ccsbBroadEn_15749 UHRF1BP1L gene, encodes complete protein.
MA620261 - JP 2018138019-A/192187: Polycomb-Associated Non-Coding RNAs.
BC003391 - Homo sapiens UHRF1 binding protein 1-like, mRNA (cDNA clone IMAGE:3447324), partial cds.
AB014601 - Homo sapiens mRNA for KIAA0701 protein, partial cds.
AL136821 - Homo sapiens mRNA; cDNA DKFZp434M1526 (from clone DKFZp434M1526).
JD285087 - Sequence 266111 from Patent EP1572962.
BX647380 - Homo sapiens mRNA; cDNA DKFZp686A1736 (from clone DKFZp686A1736).
AL833850 - Homo sapiens mRNA; cDNA DKFZp434L179 (from clone DKFZp434L179).
AK026472 - Homo sapiens cDNA: FLJ22819 fis, clone KAIA3935.
LF323449 - JP 2014500723-A/130952: Polycomb-Associated Non-Coding RNAs.
LF323447 - JP 2014500723-A/130950: Polycomb-Associated Non-Coding RNAs.
LF323446 - JP 2014500723-A/130949: Polycomb-Associated Non-Coding RNAs.
LF323445 - JP 2014500723-A/130948: Polycomb-Associated Non-Coding RNAs.
LF323444 - JP 2014500723-A/130947: Polycomb-Associated Non-Coding RNAs.
LF323443 - JP 2014500723-A/130946: Polycomb-Associated Non-Coding RNAs.
BC026286 - Homo sapiens UHRF1 binding protein 1-like, mRNA (cDNA clone IMAGE:4768469), partial cds.
LF323441 - JP 2014500723-A/130944: Polycomb-Associated Non-Coding RNAs.
LF323440 - JP 2014500723-A/130943: Polycomb-Associated Non-Coding RNAs.
LF323439 - JP 2014500723-A/130942: Polycomb-Associated Non-Coding RNAs.
LF323438 - JP 2014500723-A/130941: Polycomb-Associated Non-Coding RNAs.
LF323437 - JP 2014500723-A/130940: Polycomb-Associated Non-Coding RNAs.
MA559026 - JP 2018138019-A/130952: Polycomb-Associated Non-Coding RNAs.
MA559024 - JP 2018138019-A/130950: Polycomb-Associated Non-Coding RNAs.
MA559023 - JP 2018138019-A/130949: Polycomb-Associated Non-Coding RNAs.
MA559022 - JP 2018138019-A/130948: Polycomb-Associated Non-Coding RNAs.
MA559021 - JP 2018138019-A/130947: Polycomb-Associated Non-Coding RNAs.
MA559020 - JP 2018138019-A/130946: Polycomb-Associated Non-Coding RNAs.
MA559018 - JP 2018138019-A/130944: Polycomb-Associated Non-Coding RNAs.
MA559017 - JP 2018138019-A/130943: Polycomb-Associated Non-Coding RNAs.
MA559016 - JP 2018138019-A/130942: Polycomb-Associated Non-Coding RNAs.
MA559015 - JP 2018138019-A/130941: Polycomb-Associated Non-Coding RNAs.
MA559014 - JP 2018138019-A/130940: Polycomb-Associated Non-Coding RNAs.
JD211638 - Sequence 192662 from Patent EP1572962.
JD172719 - Sequence 153743 from Patent EP1572962.
JD441574 - Sequence 422598 from Patent EP1572962.
JD056716 - Sequence 37740 from Patent EP1572962.
JD173320 - Sequence 154344 from Patent EP1572962.
JD142156 - Sequence 123180 from Patent EP1572962.
JD441685 - Sequence 422709 from Patent EP1572962.
JD339561 - Sequence 320585 from Patent EP1572962.
JD211222 - Sequence 192246 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0JNW5, A0PJE5, BLT3B_HUMAN, BLTP3B , ENST00000279907.1, ENST00000279907.10, ENST00000279907.11, ENST00000279907.2, ENST00000279907.3, ENST00000279907.4, ENST00000279907.5, ENST00000279907.6, ENST00000279907.7, ENST00000279907.8, ENST00000279907.9, KIAA0701 , NM_015054, O75183, Q8NDL1, Q96C30, Q9BTS5, Q9H0F1, SHIP164 , uc317jso.1, uc317jso.2, UHRF1BP1L
UCSC ID: ENST00000279907.12_13
RefSeq Accession: NM_015054.2
Protein: A0JNW5 (aka UH1BL_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.