Human Gene UBE2N (ENST00000318066.7_7) from GENCODE V47lift37
  Description: ubiquitin conjugating enzyme E2 N (from RefSeq NM_003348.4)
Gencode Transcript: ENST00000318066.7_7
Gencode Gene: ENSG00000177889.10_9
Transcript (Including UTRs)
   Position: hg19 chr12:93,799,460-93,835,723 Size: 36,264 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr12:93,803,815-93,835,660 Size: 31,846 Coding Exon Count: 4 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:93,799,460-93,835,723)mRNA (may differ from genome)Protein (152 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 56.69 RPKM in Testis
Total median expression: 723.17 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -22.8063-0.362 Picture PostScript Text
3' UTR -1209.204355-0.278 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologGenome BrowserGenome Browser
Gene DetailsGene Details Gene DetailsGene DetailsGene Details
Gene SorterGene Sorter Gene SorterGene SorterGene Sorter
 RGDEnsembl WormBaseSGD
    Protein SequenceProtein Sequence
    AlignmentAlignment

-  Descriptions from all associated GenBank mRNAs
  JD488086 - Sequence 469110 from Patent EP1572962.
JD019607 - Sequence 631 from Patent EP1572962.
JD029922 - Sequence 10946 from Patent EP1572962.
JD034465 - Sequence 15489 from Patent EP1572962.
DL491658 - Novel nucleic acids.
DL490244 - Novel nucleic acids.
AK098233 - Homo sapiens cDNA FLJ40914 fis, clone UTERU2005449, weakly similar to UBIQUITIN-CONJUGATING ENZYME E2-17 KDA (EC 6.3.2.19).
AL110140 - Homo sapiens mRNA; cDNA DKFZp564A0264 (from clone DKFZp564A0264).
BC003365 - Homo sapiens ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), mRNA (cDNA clone MGC:5063 IMAGE:2900313), complete cds.
BC108704 - Homo sapiens ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), mRNA (cDNA clone MGC:131857 IMAGE:6503770), complete cds.
BC000396 - Homo sapiens ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), mRNA (cDNA clone MGC:8489 IMAGE:2822013), complete cds.
D83004 - Homo sapiens mRNA for ubiquitin-conjugating enzyme E2 UbcH-ben, complete cds.
FJ224354 - Homo sapiens epididymis secretory protein Li 71 (HEL-S-71) mRNA, complete cds.
JD466944 - Sequence 447968 from Patent EP1572962.
JD078854 - Sequence 59878 from Patent EP1572962.
JD202393 - Sequence 183417 from Patent EP1572962.
JD290190 - Sequence 271214 from Patent EP1572962.
JD512110 - Sequence 493134 from Patent EP1572962.
BT006873 - Homo sapiens ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) mRNA, complete cds.
EU176463 - Synthetic construct Homo sapiens clone IMAGE:100006526; FLH196045.01X; RZPDo839G11252D ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) (UBE2N) gene, encodes complete protein.
EU176466 - Synthetic construct Homo sapiens clone IMAGE:100006637; FLH264115.01X; RZPDo839D05257D ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) (UBE2N) gene, encodes complete protein.
DQ896763 - Synthetic construct Homo sapiens clone IMAGE:100011223; FLH196038.01L; RZPDo839C06153D ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) (UBE2N) gene, encodes complete protein.
AB464336 - Synthetic construct DNA, clone: pF1KB8112, Homo sapiens UBE2N gene for ubiquitin-conjugating enzyme E2N, without stop codon, in Flexi system.
JD065584 - Sequence 46608 from Patent EP1572962.

-  Biochemical and Signaling Pathways
  BioCyc Knowledge Library
PWY-7511 - protein ubiquitination

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000318066.1, ENST00000318066.2, ENST00000318066.3, ENST00000318066.4, ENST00000318066.5, ENST00000318066.6, hCG_38950 , HEL-S-71 , NM_003348, UBE2N , uc317qjx.1, uc317qjx.2, V9HW41, V9HW41_HUMAN
UCSC ID: ENST00000318066.7_7
RefSeq Accession: NM_003348.4

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.