Human Gene UBAC2 (ENST00000355700.9_2) from GENCODE V47lift37

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Description: UBA domain containing 2 (from HGNC UBAC2)
Gencode Transcript: ENST00000355700.9_2
Gencode Gene: ENSG00000134882.16_10
Transcript (Including UTRs)
Position: hg19 chr13:99,853,028-100,037,569 Size: 184,542 Total Exon Count: 5 Strand: +
Coding Region
Position: hg19 chr13:99,853,163-100,037,569 Size: 184,407 Coding Exon Count: 5

Page Index	Sequence and Links	Primers	MalaCards	CTD	Gene Alleles
RNA-Seq Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names	Model Information
Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr13:99,853,028-100,037,569)			mRNA (may differ from genome)		Protein (204 aa)
Gene Sorter	Genome Browser	Other Species FASTA	Gene interactions	Table Schema	AlphaFold
BioGPS	Ensembl	ExonPrimer	GeneCards	HGNC	Malacards
MGI	PubMed	UniProtKB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: UBAC2 Diseases sorted by gene-association score: behcet syndrome* (11) * = Manually curated disease association

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C016403 2,4-dinitrotoluene D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide D016604 Aflatoxin B1 D019327 Copper Sulfate D006918 Hydroxyurea D008070 Lipopolysaccharides D008770 Methylnitrosourea D013749 Tetrachlorodibenzodioxin D014303 Trinitrotoluene C028007 nickel monoxide

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 20.63 RPKM in Testis Total median expression: 539.53 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-60.60	135	-0.449	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Descriptions from all associated GenBank mRNAs


	AK290342 - Homo sapiens cDNA FLJ77865 complete cds. AK129861 - Homo sapiens cDNA FLJ26351 fis, clone HRT04754. AK075419 - Homo sapiens cDNA PSEC0110 fis, clone PLACE1010021, highly similar to Phosphoglycerate dehydrogenase like 1. AK075516 - Homo sapiens cDNA PSEC0214 fis, clone HEMBA1004100. AK300908 - Homo sapiens cDNA FLJ54852 complete cds, highly similar to Mus musculus ubiquitin associated domain containing 2 (Ubac2), mRNA. AK124404 - Homo sapiens cDNA FLJ42413 fis, clone BLADE2001141, moderately similar to Mus musculus ubiquitin associated domain containing 2 (Ubac2), mRNA. AK054563 - Homo sapiens cDNA FLJ30001 fis, clone 3NB691000018. BC121138 - Homo sapiens UBA domain containing 2, mRNA (cDNA clone IMAGE:40120986), complete cds. BC121139 - Homo sapiens UBA domain containing 2, mRNA (cDNA clone MGC:150462 IMAGE:40120987), complete cds. BC143265 - Homo sapiens cDNA clone IMAGE:9051767, with apparent retained intron. BC063559 - Homo sapiens UBA domain containing 2, mRNA (cDNA clone IMAGE:4991441), partial cds. KJ904183 - Synthetic construct Homo sapiens clone ccsbBroadEn_13577 UBAC2 gene, encodes complete protein. BC053346 - Homo sapiens phosphoglycerate dehydrogenase like 1, mRNA (cDNA clone IMAGE:5174876), partial cds. AK055110 - Homo sapiens cDNA FLJ30548 fis, clone BRAWH2001461, highly similar to Mus musculus ubiquitin associated domain containing 2 (Ubac2), mRNA. BC072674 - Homo sapiens UBA domain containing 2, mRNA (cDNA clone IMAGE:5756018), complete cds. AF339812 - Homo sapiens clone IMAGE:29333, mRNA sequence. CU687244 - Synthetic construct Homo sapiens gateway clone IMAGE:100022948 5' read UBAC2 mRNA. KJ904182 - Synthetic construct Homo sapiens clone ccsbBroadEn_13576 UBAC2 gene, encodes complete protein.

Other Names for This Gene


	Alternate Gene Symbols: AK290342, ENST00000355700.1, ENST00000355700.2, ENST00000355700.3, ENST00000355700.4, ENST00000355700.5, ENST00000355700.6, ENST00000355700.7, ENST00000355700.8, UBAC2 , uc317zfe.1, X6R5E5, X6R5E5_HUMAN UCSC ID: ENST00000355700.9_2 RefSeq Accession: NM_001144072.2

Gene Model Information


	Click here for a detailed description of the fields of the table above.

Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.