The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P17752
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0004497 monooxygenase activity GO:0004510 tryptophan 5-monooxygenase activity GO:0005506 iron ion binding GO:0016491 oxidoreductase activity GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0046872 metal ion binding
Biological Process: GO:0007623 circadian rhythm GO:0009072 aromatic amino acid family metabolic process GO:0030279 negative regulation of ossification GO:0035902 response to immobilization stress GO:0042427 serotonin biosynthetic process GO:0045600 positive regulation of fat cell differentiation GO:0046849 bone remodeling GO:0055114 oxidation-reduction process GO:0060749 mammary gland alveolus development