ID:SPG17_HUMAN DESCRIPTION: RecName: Full=Sperm-associated antigen 17; AltName: Full=Projection protein PF6 homolog; FUNCTION: Seems to be important for the structural integrity of the central apparatus of the sperm axoneme (By similarity). SUBUNIT: Interacts (via the C-terminus) with SPAG6; the interaction probably occurs on polymerized microtubules (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cytoplasm, cytoskeleton, flagellum axoneme (By similarity). Note=Detected in the cytoplasm of round spermatids and in condensing spermatids. Localized to the central pair of the sperm flagellar axoneme. Colocalizes with SPAG6 on microtubules (By similarity). TISSUE SPECIFICITY: Highly expressed in testis. Expressed in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6Q759
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
