The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8IW75
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0010466 negative regulation of peptidase activity GO:0010951 negative regulation of endopeptidase activity GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling GO:0045721 negative regulation of gluconeogenesis GO:0046628 positive regulation of insulin receptor signaling pathway GO:0051055 negative regulation of lipid biosynthetic process GO:0090181 regulation of cholesterol metabolic process GO:0090207 regulation of triglyceride metabolic process
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
