ID:SCAPE_HUMAN DESCRIPTION: RecName: Full=S phase cyclin A-associated protein in the endoplasmic reticulum; Short=S phase cyclin A-associated protein in the ER; AltName: Full=Zinc finger protein 291; FUNCTION: CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm. SUBUNIT: Interacts with CCNA2/CDK2 complex, but not with CCNA2/CDC2, CCNB1/CDC2 or CCNE1/CDK2 complexes, at multiple phases of the cell cycle, including S and G2/M. SUBCELLULAR LOCATION: Endoplasmic reticulum. Nucleus. Note=Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus. TISSUE SPECIFICITY: Widely expressed with highest expression in testis. DEVELOPMENTAL STAGE: Expressed at each stage of the cell cycle, including G0, although the expression is somewhat higher in late G1 and S phases. PTM: Phosphorylated in vitro by the CCNA2/CDK2 complex. SIMILARITY: Contains 1 C2H2-type zinc finger. SEQUENCE CAUTION: Sequence=AAG47945.1; Type=Erroneous initiation; Sequence=AAH15212.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9BY12
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
