ID:RNF17_HUMAN DESCRIPTION: RecName: Full=RING finger protein 17; AltName: Full=Tudor domain-containing protein 4; FUNCTION: Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity). SUBUNIT: Interacts with MXD1, MXD3, MXD4, MXI1 and PIWIL1. Self- associates (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly found in the cytoplasm. Component of a nuage in male germ cells (an electron-dense spherical cytoplasmic body present in late pachytene and diplotene spermatocytes and in elonging spermatids) (By similarity). TISSUE SPECIFICITY: Testis specific. SIMILARITY: Contains 1 RING-type zinc finger. SIMILARITY: Contains 4 Tudor domains. SEQUENCE CAUTION: Sequence=AAH64847.1; Type=Erroneous initiation; Sequence=BAA91972.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9BXT8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
BC037275 - Homo sapiens cDNA clone IMAGE:5266526, **** WARNING: chimeric clone ****. BC146822 - Homo sapiens cDNA clone MGC:167101 IMAGE:8860434. AK302405 - Homo sapiens cDNA FLJ61720 complete cds, highly similar to Homo sapiens ring finger protein 17 (RNF17), mRNA. AK302435 - Homo sapiens cDNA FLJ61721 complete cds, highly similar to Homo sapiens ring finger protein 17 (RNF17), mRNA. BC048962 - Homo sapiens cDNA clone IMAGE:4823672, **** WARNING: chimeric clone ****. BC166669 - Synthetic construct Homo sapiens clone IMAGE:100066395, MGC:195532 ring finger protein 17 (RNF17) mRNA, encodes complete protein. BC064847 - Homo sapiens ring finger protein 17, mRNA (cDNA clone IMAGE:30387200), complete cds. AK001907 - Homo sapiens cDNA FLJ11045 fis, clone PLACE1004460. AF285603 - Homo sapiens ring finger protein 17 short isoform (RNF17) mRNA, complete cds. AF285602 - Homo sapiens ring finger protein 17 long isoform (RNF17) mRNA, complete cds.
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
