ID:RGPD4_HUMAN DESCRIPTION: RecName: Full=RanBP2-like and GRIP domain-containing protein 4; MISCELLANEOUS: One of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere. SIMILARITY: Contains 1 GRIP domain. SIMILARITY: Contains 2 RanBD1 domains. SIMILARITY: Contains 2 TPR repeats.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q7Z3J3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0008536 Ran GTPase binding GO:0005096 GTPase activator activity
Biological Process: GO:0000082 G1/S transition of mitotic cell cycle GO:0006405 RNA export from nucleus GO:0006511 ubiquitin-dependent protein catabolic process GO:0006606 protein import into nucleus GO:0007051 spindle organization GO:0043547 positive regulation of GTPase activity GO:0046604 positive regulation of mitotic centrosome separation GO:0046907 intracellular transport