Human Gene RGN (ENST00000397180.6_5) from GENCODE V47lift37

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Description: regucalcin, transcript variant 2 (from RefSeq NM_152869.4)
Gencode Transcript: ENST00000397180.6_5
Gencode Gene: ENSG00000130988.13_8
Transcript (Including UTRs)
Position: hg19 chrX:46,937,842-46,952,712 Size: 14,871 Total Exon Count: 8 Strand: +
Coding Region
Position: hg19 chrX:46,940,544-46,952,346 Size: 11,803 Coding Exon Count: 6

Page Index	Sequence and Links	Primers	CTD	Gene Alleles	RNA-Seq Expression
Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names	Model Information
Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chrX:46,937,842-46,952,712)			mRNA (may differ from genome)		Protein (299 aa)
Gene Sorter	Genome Browser	Other Species FASTA	Gene interactions	Table Schema	AlphaFold
BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards	HGNC
MGI	OMIM	PubMed	UniProtKB	Wikipedia	BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen D016604 Aflatoxin B1 D002994 Clofibrate D003300 Copper D016572 Cyclosporine D013749 Tetrachlorodibenzodioxin C006253 pirinixic acid C016104 sodium bichromate C049325 1,2-dithiol-3-thione C576882 1-(2-trifluoromethoxyphenyl)-2-nitroethanone more ... click here to view the complete list

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 84.94 RPKM in Adrenal Gland Total median expression: 392.42 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-309.30	902	-0.343	Picture	PostScript	Text
3' UTR	-87.40	366	-0.239	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Descriptions from all associated GenBank mRNAs


	AK223360 - Homo sapiens mRNA for regucalcin variant, clone: FCC101A02. BC050371 - Homo sapiens regucalcin (senescence marker protein-30), mRNA (cDNA clone MGC:51842 IMAGE:5760604), complete cds. BC058880 - Homo sapiens regucalcin (senescence marker protein-30), mRNA (cDNA clone IMAGE:5731957), partial cds. AK290136 - Homo sapiens cDNA FLJ75608 complete cds, highly similar to Homo sapiens regucalcin (senescence marker protein-30) (RGN),transcript variant 1, mRNA. BC073173 - Homo sapiens regucalcin (senescence marker protein-30), mRNA (cDNA clone MGC:87766 IMAGE:6186669), complete cds. AB032064 - Homo sapiens mRNA for regucalcin, complete cds. EU794655 - Homo sapiens epididymis secretory protein Li 41 (HEL-S-41) mRNA, complete cds. JD461393 - Sequence 442417 from Patent EP1572962. JD475113 - Sequence 456137 from Patent EP1572962. JD252561 - Sequence 233585 from Patent EP1572962. JD096726 - Sequence 77750 from Patent EP1572962. AB028125 - Homo sapiens mRNA for regucalcin, complete cds. JD316048 - Sequence 297072 from Patent EP1572962. D31815 - Homo sapiens mRNA for SMP-30 (senescence marker protein-30), complete cds. E09013 - cDNA encoding human-SMP30 protein. JD303390 - Sequence 284414 from Patent EP1572962. KJ892688 - Synthetic construct Homo sapiens clone ccsbBroadEn_02082 RGN gene, encodes complete protein.

Other Names for This Gene


	Alternate Gene Symbols: ENST00000397180.1, ENST00000397180.2, ENST00000397180.3, ENST00000397180.4, ENST00000397180.5, HEL-S-41 , NM_152869, uc318yuw.1, uc318yuw.2, V9HWF8, V9HWF8_HUMAN UCSC ID: ENST00000397180.6_5 RefSeq Accession: NM_152869.4

Gene Model Information


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Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.