Human Gene PSME3 (ENST00000590720.6_7) from GENCODE V47lift37
  Description: proteasome activator subunit 3, transcript variant 4 (from RefSeq NR_049772.2)
Gencode Transcript: ENST00000590720.6_7
Gencode Gene: ENSG00000131467.12_13
Transcript (Including UTRs)
   Position: hg19 chr17:40,985,414-40,995,777 Size: 10,364 Total Exon Count: 11 Strand: +
Coding Region
   Position: hg19 chr17:40,985,649-40,993,595 Size: 7,947 Coding Exon Count: 11 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:40,985,414-40,995,777)mRNA (may differ from genome)Protein (254 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
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-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 32.95 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 798.52 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -108.60235-0.462 Picture PostScript Text
3' UTR -653.802182-0.300 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologGenome BrowserNo ortholog
Gene DetailsGene Details Gene DetailsGene Details 
Gene SorterGene Sorter Gene SorterGene Sorter 
 RGDEnsembl WormBase 
    Protein Sequence 
    Alignment 

-  Descriptions from all associated GenBank mRNAs
  AK057221 - Homo sapiens cDNA FLJ32659 fis, clone TESTI1000045, highly similar to Proteasome activator complex subunit 3.
LF209350 - JP 2014500723-A/16853: Polycomb-Associated Non-Coding RNAs.
AK314347 - Homo sapiens cDNA, FLJ95110.
AK307110 - Homo sapiens cDNA, FLJ97058.
BC001423 - Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki), mRNA (cDNA clone MGC:1394 IMAGE:3139753), complete cds.
EU794653 - Homo sapiens epididymis secretory protein Li 283 (HEL-S-283) mRNA, complete cds.
BX640801 - Homo sapiens mRNA; cDNA DKFZp686J2076 (from clone DKFZp686J2076).
AK292618 - Homo sapiens cDNA FLJ78054 complete cds, highly similar to Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3), transcript variant 1, mRNA.
BC002684 - Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki), mRNA (cDNA clone MGC:3572 IMAGE:3606558), complete cds.
JD067261 - Sequence 48285 from Patent EP1572962.
AK303211 - Homo sapiens cDNA FLJ57249 complete cds, highly similar to Proteasome activator complex subunit 3.
AK074999 - Homo sapiens cDNA FLJ90518 fis, clone NT2RP3004557, highly similar to Proteasome activator complex subunit 3.
LF327916 - JP 2014500723-A/135419: Polycomb-Associated Non-Coding RNAs.
JD195732 - Sequence 176756 from Patent EP1572962.
U11292 - Homo sapiens Ki nuclear autoantigen mRNA, complete cds.
JD462229 - Sequence 443253 from Patent EP1572962.
JD057644 - Sequence 38668 from Patent EP1572962.
BC008020 - Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki), mRNA (cDNA clone MGC:15945 IMAGE:3537911), complete cds.
JD445538 - Sequence 426562 from Patent EP1572962.
JD343272 - Sequence 324296 from Patent EP1572962.
JD519415 - Sequence 500439 from Patent EP1572962.
AB528620 - Synthetic construct DNA, clone: pF1KB6359, Homo sapiens PSME3 gene for proteasome (prosome, macropain) activator subunit 3, without stop codon, in Flexi system.
DQ891930 - Synthetic construct clone IMAGE:100004560; FLH181520.01X; RZPDo839E04136D proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3) gene, encodes complete protein.
DQ895117 - Synthetic construct Homo sapiens clone IMAGE:100009577; FLH181516.01L; RZPDo839E04135D proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3) gene, encodes complete protein.
CU678118 - Synthetic construct Homo sapiens gateway clone IMAGE:100018614 5' read PSME3 mRNA.
KJ892954 - Synthetic construct Homo sapiens clone ccsbBroadEn_02348 PSME3 gene, encodes complete protein.
BT019386 - Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) mRNA, complete cds.
CR541745 - Homo sapiens full open reading frame cDNA clone RZPDo834H0629D for gene PSME3, proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki); complete cds, incl. stopcodon.
FJ200488 - Homo sapiens REG gamma-3 variant mRNA, complete cds.
JX156303 - Homo sapiens PA28 gamma variant 5 mRNA, complete cds, alternatively spliced.
JD160410 - Sequence 141434 from Patent EP1572962.
JD552520 - Sequence 533544 from Patent EP1572962.
JD087410 - Sequence 68434 from Patent EP1572962.
JD524256 - Sequence 505280 from Patent EP1572962.
JD297979 - Sequence 279003 from Patent EP1572962.
JD083813 - Sequence 64837 from Patent EP1572962.
JD551245 - Sequence 532269 from Patent EP1572962.
JD358351 - Sequence 339375 from Patent EP1572962.
JD290068 - Sequence 271092 from Patent EP1572962.
JD390715 - Sequence 371739 from Patent EP1572962.
JD418466 - Sequence 399490 from Patent EP1572962.
JD203496 - Sequence 184520 from Patent EP1572962.
JD404437 - Sequence 385461 from Patent EP1572962.
JD163923 - Sequence 144947 from Patent EP1572962.
JD555658 - Sequence 536682 from Patent EP1572962.
JD092648 - Sequence 73672 from Patent EP1572962.
JD252024 - Sequence 233048 from Patent EP1572962.
JD449057 - Sequence 430081 from Patent EP1572962.
JD020816 - Sequence 1840 from Patent EP1572962.
JD032767 - Sequence 13791 from Patent EP1572962.
JD410016 - Sequence 391040 from Patent EP1572962.
JD551938 - Sequence 532962 from Patent EP1572962.
JD110230 - Sequence 91254 from Patent EP1572962.
JD251193 - Sequence 232217 from Patent EP1572962.
JD402079 - Sequence 383103 from Patent EP1572962.
JD398829 - Sequence 379853 from Patent EP1572962.
JD133505 - Sequence 114529 from Patent EP1572962.
JD545443 - Sequence 526467 from Patent EP1572962.
JD279000 - Sequence 260024 from Patent EP1572962.
JD064424 - Sequence 45448 from Patent EP1572962.
JD218701 - Sequence 199725 from Patent EP1572962.
JD300884 - Sequence 281908 from Patent EP1572962.
JD354720 - Sequence 335744 from Patent EP1572962.
JD433405 - Sequence 414429 from Patent EP1572962.
JD435276 - Sequence 416300 from Patent EP1572962.
JD257175 - Sequence 238199 from Patent EP1572962.
JD281110 - Sequence 262134 from Patent EP1572962.
JD460431 - Sequence 441455 from Patent EP1572962.
JD284978 - Sequence 266002 from Patent EP1572962.
JD429858 - Sequence 410882 from Patent EP1572962.
JD527455 - Sequence 508479 from Patent EP1572962.
JD299572 - Sequence 280596 from Patent EP1572962.
JD563668 - Sequence 544692 from Patent EP1572962.
JD294382 - Sequence 275406 from Patent EP1572962.
JD464250 - Sequence 445274 from Patent EP1572962.
JD402333 - Sequence 383357 from Patent EP1572962.
JD322353 - Sequence 303377 from Patent EP1572962.
JD283872 - Sequence 264896 from Patent EP1572962.
LF209352 - JP 2014500723-A/16855: Polycomb-Associated Non-Coding RNAs.
JD229451 - Sequence 210475 from Patent EP1572962.
JD299988 - Sequence 281012 from Patent EP1572962.
JD297639 - Sequence 278663 from Patent EP1572962.
JD202841 - Sequence 183865 from Patent EP1572962.
JD503862 - Sequence 484886 from Patent EP1572962.
MA563493 - JP 2018138019-A/135419: Polycomb-Associated Non-Coding RNAs.
MA444927 - JP 2018138019-A/16853: Polycomb-Associated Non-Coding RNAs.
MA444929 - JP 2018138019-A/16855: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000590720.1, ENST00000590720.2, ENST00000590720.3, ENST00000590720.4, ENST00000590720.5, HEL-S-283 , NR_049772, uc326vll.1, uc326vll.2, V9HWJ8, V9HWJ8_HUMAN
UCSC ID: ENST00000590720.6_7
RefSeq Accession: NM_005789.4

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.