Human Gene PRLH (ENST00000165524.1_4) from GENCODE V47lift37
  Description: prolactin releasing hormone (from RefSeq NM_015893.1)
Gencode Transcript: ENST00000165524.1_4
Gencode Gene: ENSG00000071677.1_7
Transcript (Including UTRs)
   Position: hg19 chr2:238,475,217-238,475,818 Size: 602 Total Exon Count: 2 Strand: +
Coding Region
   Position: hg19 chr2:238,475,217-238,475,818 Size: 602 Coding Exon Count: 2 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr2:238,475,217-238,475,818)mRNA (may differ from genome)Protein (87 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsHGNC
MGIOMIMPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.14 RPKM in Heart - Atrial Appendage
Total median expression: 0.19 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026194 - PrRP

Pfam Domains:
PF15172 - Prolactin-releasing peptide

ModBase Predicted Comparative 3D Structure on Q53QV7
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0031861 prolactin-releasing peptide receptor binding

Biological Process:
GO:0001894 tissue homeostasis
GO:0002021 response to dietary excess
GO:0002023 reduction of food intake in response to dietary excess
GO:0006112 energy reserve metabolic process
GO:0006629 lipid metabolic process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007631 feeding behavior
GO:0009749 response to glucose
GO:0010469 regulation of receptor activity
GO:0032868 response to insulin
GO:0040014 regulation of multicellular organism growth
GO:0042755 eating behavior
GO:0043434 response to peptide hormone
GO:0045444 fat cell differentiation
GO:0048483 autonomic nervous system development

Cellular Component:
GO:0005737 cytoplasm


-  Descriptions from all associated GenBank mRNAs
  AB015419 - Homo sapiens mRNA for preproprolactin-releasing peptide, complete cds.
BC069081 - Homo sapiens prolactin releasing hormone, mRNA (cDNA clone MGC:95356 IMAGE:7216895), complete cds.
BC069284 - Homo sapiens prolactin releasing hormone, mRNA (cDNA clone MGC:97403 IMAGE:7262679), complete cds.
LF205303 - JP 2014500723-A/12806: Polycomb-Associated Non-Coding RNAs.
MA440880 - JP 2018138019-A/12806: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: hCG_23020 , NM_015893, PRH , PRLH , Q53QV7, Q53QV7_HUMAN, uc317cde.1, uc317cde.2
UCSC ID: ENST00000165524.1_4
RefSeq Accession: NM_015893.1
Protein: Q53QV7

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.