ID:PLP2_HUMAN DESCRIPTION: RecName: Full=Proteolipid protein 2; AltName: Full=Differentiation-dependent protein A4; AltName: Full=Intestinal membrane A4 protein; FUNCTION: May play a role in cell differentiation in the intestinal epithelium. INTERACTION: P32246:CCR1; NbExp=3; IntAct=EBI-608347, EBI-608322; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt. SIMILARITY: Contains 1 MARVEL domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q04941
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.