ID:NUBP2_HUMAN DESCRIPTION: RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2; AltName: Full=Nucleotide-binding protein 2; Short=NBP 2; FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins (By similarity). SUBUNIT: Interacts with KIFC1 (By similarity). Interacts with NUBP1. SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm, cytoskeleton, centrosome (By similarity). Note=Enriched at the centrosomes during mitosis (By similarity). TISSUE SPECIFICITY: Widely expressed with highest expression in skeletal muscle. DEVELOPMENTAL STAGE: Expressed in fetal brain, lung, liver and kidney. SIMILARITY: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9Y5Y2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
