Human Gene NSA2 (ENST00000610426.5_5) from GENCODE V47lift37
  Description: NSA2 ribosome biogenesis factor, transcript variant 6 (from RefSeq NR_157206.2)
Gencode Transcript: ENST00000610426.5_5
Gencode Gene: ENSG00000164346.10_12
Transcript (Including UTRs)
   Position: hg19 chr5:74,063,074-74,075,938 Size: 12,865 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr5:74,063,186-74,072,496 Size: 9,311 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersCTDGene AllelesMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:74,063,074-74,075,938)mRNA (may differ from genome)Protein (260 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -41.00112-0.366 Picture PostScript Text
3' UTR -674.083442-0.196 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR022309 - Ribosomal_S8e/biogenesis_NSA2

Pfam Domains:
PF01201 - Ribosomal protein S8e

ModBase Predicted Comparative 3D Structure on Q5J7U2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologGenome BrowserGenome Browser
Gene DetailsGene Details Gene DetailsGene DetailsGene Details
Gene SorterGene Sorter Gene SorterGene SorterGene Sorter
 RGDEnsembl WormBaseSGD
    Protein SequenceProtein Sequence
    AlignmentAlignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  LF213629 - JP 2014500723-A/21132: Polycomb-Associated Non-Coding RNAs.
BC005288 - Homo sapiens TGF beta-inducible nuclear protein 1, mRNA (cDNA clone MGC:12345 IMAGE:3683720), complete cds.
AK313784 - Homo sapiens cDNA, FLJ94393, Homo sapiens TGF beta-inducible nuclear protein 1 (TINP1), mRNA.
AF372458 - Homo sapiens hairy cell leukemia protein 1 mRNA, complete cds.
AF077615 - Homo sapiens TGF beta inducible nuclear protein TINP1 (TINP1) mRNA, complete cds.
AJ012409 - Homo sapiens mRNA for hypothetical protein, clone YR-29.
CU675085 - Synthetic construct Homo sapiens gateway clone IMAGE:100018641 5' read TINP1 mRNA.
HQ447386 - Synthetic construct Homo sapiens clone IMAGE:100070707; CCSB005478_02 TGF beta-inducible nuclear protein 1 (TINP1) gene, encodes complete protein.
KJ898206 - Synthetic construct Homo sapiens clone ccsbBroadEn_07600 NSA2 gene, encodes complete protein.
AY443419 - Homo sapiens TGF-beta inducible nuclear protein (CDK105) mRNA, complete cds.
JD214231 - Sequence 195255 from Patent EP1572962.
JD312386 - Sequence 293410 from Patent EP1572962.
MA449206 - JP 2018138019-A/21132: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: CDK105 , ENST00000610426.1, ENST00000610426.2, ENST00000610426.3, ENST00000610426.4, hCG_38199 , NR_157206, Q5J7U2, Q5J7U2_HUMAN, TINP1 , uc327mtq.1, uc327mtq.2
UCSC ID: ENST00000610426.5_5
RefSeq Accession: NM_014886.6
Protein: Q5J7U2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.