Human Gene MRPL45 (ENST00000613675.5_4) from GENCODE V47lift37

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Description: mitochondrial ribosomal protein L45, transcript variant 1 (from RefSeq NM_032351.6)
Gencode Transcript: ENST00000613675.5_4
Gencode Gene: ENSG00000278845.5_7
Transcript (Including UTRs)
Position: hg19 chr17:36,453,134-36,479,094 Size: 25,961 Total Exon Count: 8 Strand: +
Coding Region
Position: hg19 chr17:36,453,150-36,478,478 Size: 25,329 Coding Exon Count: 8

Page Index	Sequence and Links	Primers	CTD	Gene Alleles	RNA Structure
Other Species	mRNA Descriptions	Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr17:36,453,134-36,479,094)			mRNA (may differ from genome)		Protein (306 aa)
Gene Sorter	Genome Browser	Other Species FASTA	Gene interactions	Table Schema	AlphaFold
BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards	HGNC
MGI	OMIM	PubMed	UniProtKB	BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C016403 2,4-dinitrotoluene C023514 2,6-dinitrotoluene C009505 4,4'-diaminodiphenylmethane C082164 4-methoxycinnamate methyl ester D015127 9,10-Dimethyl-1,2-benzanthracene D000082 Acetaminophen D002994 Clofibrate D004147 Dioxins D004365 Drugs, Chinese Herbal D000431 Ethanol more ... click here to view the complete list

Common Gene Haplotype Alleles


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-1.00	16	-0.062	Picture	PostScript	Text
3' UTR	-170.50	616	-0.277	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	Genome Browser	No ortholog
Gene Details	Gene Details		Gene Details	Gene Details
Gene Sorter	Gene Sorter		Gene Sorter	Gene Sorter
	RGD	Ensembl		WormBase
				Protein Sequence
				Alignment

Descriptions from all associated GenBank mRNAs


	AK293605 - Homo sapiens cDNA FLJ61100 complete cds, highly similar to 39S ribosomal protein L45, mitochondrial precursor. BC130382 - Homo sapiens mitochondrial ribosomal protein L45, mRNA (cDNA clone MGC:163254 IMAGE:40146413), complete cds. BC130384 - Homo sapiens mitochondrial ribosomal protein L45, mRNA (cDNA clone MGC:163256 IMAGE:40146415), complete cds. AK225031 - Homo sapiens mRNA for 39S ribosomal protein L45, mitochondrial precursor variant, clone: adKA01604. AK172741 - Homo sapiens cDNA FLJ23902 fis, clone ADKA01604. BC105297 - Homo sapiens cDNA clone IMAGE:6387768, partial cds. HQ258365 - Synthetic construct Homo sapiens clone IMAGE:100072794 mitochondrial ribosomal protein L45 (MRPL45) gene, encodes complete protein; nuclear gene for mitochondrial product. KJ899786 - Synthetic construct Homo sapiens clone ccsbBroadEn_09180 MRPL45 gene, encodes complete protein. BC006235 - Homo sapiens cDNA clone IMAGE:3951804, containing frame-shift errors. KJ903411 - Synthetic construct Homo sapiens clone ccsbBroadEn_12805 MRPL45 gene, encodes complete protein. JD062027 - Sequence 43051 from Patent EP1572962. JD523973 - Sequence 504997 from Patent EP1572962. JD194527 - Sequence 175551 from Patent EP1572962. JD111066 - Sequence 92090 from Patent EP1572962. JD222738 - Sequence 203762 from Patent EP1572962. JD252005 - Sequence 233029 from Patent EP1572962. JD433745 - Sequence 414769 from Patent EP1572962. JD267002 - Sequence 248026 from Patent EP1572962. JD155652 - Sequence 136676 from Patent EP1572962. JD391130 - Sequence 372154 from Patent EP1572962. JD483560 - Sequence 464584 from Patent EP1572962. JD175139 - Sequence 156163 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A0A087X2D5, A0A087X2D5_HUMAN, ENST00000613675.1, ENST00000613675.2, ENST00000613675.3, ENST00000613675.4, MRPL45 , NM_032351, uc327oto.1, uc327oto.2 UCSC ID: ENST00000613675.5_4 RefSeq Accession: NM_032351.6

Gene Model Information


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Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.