The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF09812 - Mitochondrial ribosomal protein L28
ModBase Predicted Comparative 3D Structure on Q9NQ50
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
DQ894633 - Synthetic construct Homo sapiens clone IMAGE:100009093; FLH177089.01L; RZPDo839C12123D mitochondrial ribosomal protein L40 (MRPL40) gene, encodes complete protein; nuclear gene for mitochondrial product. DQ891455 - Synthetic construct clone IMAGE:100004085; FLH177092.01X; RZPDo839C12124D mitochondrial ribosomal protein L40 (MRPL40) gene, encodes complete protein; nuclear gene for mitochondrial product. DQ891653 - Synthetic construct Homo sapiens clone IMAGE:100004283; FLH263503.01X; RZPDo839B09130D mitochondrial ribosomal protein L40 (MRPL40) gene, encodes complete protein; nuclear gene for mitochondrial product. LF210543 - JP 2014500723-A/18046: Polycomb-Associated Non-Coding RNAs. AK123768 - Homo sapiens cDNA FLJ41774 fis, clone IMR322011689, highly similar to 39S ribosomal protein L40, mitochondrial precursor. BC009707 - Homo sapiens mitochondrial ribosomal protein L40, mRNA (cDNA clone MGC:9400 IMAGE:3876531), complete cds. AF034091 - Homo sapiens nuclear localization signal containing protein deleted in Velo-Cardio-Facial syndrome (Nlvcf) mRNA, complete cds. AJ295637 - Homo sapiens mRNA for URIM protein. CR456532 - Homo sapiens NLVCF full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.NLVCF). AB528186 - Synthetic construct DNA, clone: pF1KE0533, Homo sapiens MRPL40 gene for mitochondrial ribosomal protein L40, without stop codon, in Flexi system. CU013420 - Homo sapiens MRPL40, mRNA (cDNA clone IMAGE:100000389), complete cds, without stop codon, in Gateway system. CU013132 - Homo sapiens MRPL40, mRNA (cDNA clone IMAGE:100000485), complete cds, with stop codon, in Gateway system. AK057708 - Homo sapiens cDNA FLJ33146 fis, clone UTERU2000197, moderately similar to Homo sapiens nuclear localization signal containing protein deleted in Velo-Cardio-Facial syndrome (Nlvcf) mRNA. LF338649 - JP 2014500723-A/146152: Polycomb-Associated Non-Coding RNAs. JD489181 - Sequence 470205 from Patent EP1572962. MA446120 - JP 2018138019-A/18046: Polycomb-Associated Non-Coding RNAs. MA574226 - JP 2018138019-A/146152: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9NQ50 (Reactome details) participates in the following event(s):
R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA R-HSA-5368286 Mitochondrial translation initiation R-HSA-5419276 Mitochondrial translation termination R-HSA-5368287 Mitochondrial translation R-HSA-5389840 Mitochondrial translation elongation R-HSA-72766 Translation R-HSA-392499 Metabolism of proteins
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
