Human Gene KRTAP29-1 (ENST00000391353.1_6) from GENCODE V47lift37
  Description: keratin associated like protein 29-1 (from RefSeq NM_001257309.1)
Gencode Transcript: ENST00000391353.1_6
Gencode Gene: ENSG00000212658.1_8
Transcript (Including UTRs)
   Position: hg19 chr17:39,458,078-39,459,103 Size: 1,026 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr17:39,458,078-39,459,103 Size: 1,026 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsPathways
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:39,458,078-39,459,103)mRNA (may differ from genome)Protein (341 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsHGNC
MGIPubMedReactomeUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: KR291_HUMAN
DESCRIPTION: RecName: Full=Keratin-associated protein 29-1; AltName: Full=Keratin-associated protein 29.2;
SIMILARITY: Belongs to the KRTAP type 10 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.04 RPKM in Spleen
Total median expression: 0.13 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  Protein Domain and Structure Information
  Pfam Domains:
PF13885 - Keratin, high sulfur B2 protein

SCOP Domains:
56281 - Metallo-hydrolase/oxidoreductase

ModBase Predicted Comparative 3D Structure on A8MX34
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0031424 keratinization

Cellular Component:
GO:0005829 cytosol
GO:0005882 intermediate filament
GO:0045095 keratin filament


-  Descriptions from all associated GenBank mRNAs
 

-  Biochemical and Signaling Pathways
  Reactome (by CSHL, EBI, and GO)

Protein A8MX34 (Reactome details) participates in the following event(s):

R-HSA-6805567 Keratinization
R-HSA-1266738 Developmental Biology

-  Other Names for This Gene
  Alternate Gene Symbols: A8MX34, KAP29.2, KR291_HUMAN, NM_001257309, uc318ult.1, uc318ult.2
UCSC ID: ENST00000391353.1_6
RefSeq Accession: NM_001257309.1
Protein: A8MX34 (aka KR291_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.