Human Gene KIF5C (ENST00000435030.1) from GENCODE V47lift37
Description: kinesin family member 5C (from HGNC KIF5C)Gencode Transcript: ENST00000435030.1Gencode Gene: ENSG00000168280.12Transcript (Including UTRs) Position: hg19 chr2:149,632,819-149,883,273 Size: 250,455 Total Exon Count: 26 Strand: +Coding Region Position: hg19 chr2:149,633,187-149,868,190 Size: 235,004 Coding Exon Count: 25
Data last updated at UCSC: 2024-08-22 23:36:26
Sequence and Links to Tools and Databases
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00225 - Kinesin motor domainPF16796 - Microtubule bindingSCOP Domains: 52540 - P-loop containing nucleoside triphosphate hydrolasesModBase Predicted Comparative 3D Structure on Q9UFW7 The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0003777 microtubule motor activityBiological Process: GO:0007018 microtubule-based movement
Descriptions from all associated GenBank mRNAs
BC002721 - Homo sapiens kinesin family member 5C, mRNA (cDNA clone IMAGE:3627474), partial cds.BC025961 - Homo sapiens kinesin family member 5C, mRNA (cDNA clone IMAGE:3627269), partial cds.AB011103 - Homo sapiens KIAA0531 mRNA for KIAA0531 protein.BC017298 - Homo sapiens kinesin family member 5C, mRNA (cDNA clone IMAGE:5017583), partial cds.AB384491 - Synthetic construct DNA, clone: pF1KA0531, Homo sapiens KIF5C gene for kinesin family member 5C, complete cds, without stop codon, in Flexi system.BC127772 - Homo sapiens kinesin family member 5C, mRNA (cDNA clone IMAGE:40128992), partial cds.BC110287 - Homo sapiens kinesin family member 5C, mRNA (cDNA clone MGC:111478 IMAGE:5165262), complete cds.KJ904493 - Synthetic construct Homo sapiens clone ccsbBroadEn_13887 KIF5C gene, encodes complete protein.JD485612 - Sequence 466636 from Patent EP1572962.JD109013 - Sequence 90037 from Patent EP1572962.JD109014 - Sequence 90038 from Patent EP1572962.JD472988 - Sequence 454012 from Patent EP1572962.JD394991 - Sequence 376015 from Patent EP1572962.JD256380 - Sequence 237404 from Patent EP1572962.AB073396 - Homo sapiens primary neuroblastoma cDNA, clone:Nbla04137, full insert sequence.AB209191 - Homo sapiens mRNA for Kinesin heavy chain isoform 5C variant protein.AL117393 - Homo sapiens mRNA; cDNA DKFZp566O183 (from clone DKFZp566O183).AK126689 - Homo sapiens cDNA FLJ44735 fis, clone BRACE3026456.JD552721 - Sequence 533745 from Patent EP1572962.JD532754 - Sequence 513778 from Patent EP1572962.JD044394 - Sequence 25418 from Patent EP1572962.AL050070 - Homo sapiens mRNA; cDNA DKFZp566B0746 (from clone DKFZp566B0746).JD471690 - Sequence 452714 from Patent EP1572962.JD369482 - Sequence 350506 from Patent EP1572962.JD312974 - Sequence 293998 from Patent EP1572962.JD256026 - Sequence 237050 from Patent EP1572962.JD036370 - Sequence 17394 from Patent EP1572962.JD529000 - Sequence 510024 from Patent EP1572962.JD203113 - Sequence 184137 from Patent EP1572962.JD200247 - Sequence 181271 from Patent EP1572962.JD247252 - Sequence 228276 from Patent EP1572962.JD290517 - Sequence 271541 from Patent EP1572962.JD085366 - Sequence 66390 from Patent EP1572962.JD381333 - Sequence 362357 from Patent EP1572962.JD299839 - Sequence 280863 from Patent EP1572962.JD531175 - Sequence 512199 from Patent EP1572962.JD379311 - Sequence 360335 from Patent EP1572962.JD048184 - Sequence 29208 from Patent EP1572962.JD327728 - Sequence 308752 from Patent EP1572962.JD360850 - Sequence 341874 from Patent EP1572962.JD245298 - Sequence 226322 from Patent EP1572962.JD298175 - Sequence 279199 from Patent EP1572962.JD299685 - Sequence 280709 from Patent EP1572962.JD098051 - Sequence 79075 from Patent EP1572962.JD354612 - Sequence 335636 from Patent EP1572962.JD417415 - Sequence 398439 from Patent EP1572962.JD059012 - Sequence 40036 from Patent EP1572962.JD052060 - Sequence 33084 from Patent EP1572962.JD241268 - Sequence 222292 from Patent EP1572962.JD468658 - Sequence 449682 from Patent EP1572962.JD261759 - Sequence 242783 from Patent EP1572962.JD241151 - Sequence 222175 from Patent EP1572962.JD333491 - Sequence 314515 from Patent EP1572962.JD146711 - Sequence 127735 from Patent EP1572962.JD302131 - Sequence 283155 from Patent EP1572962.AF010146 - Homo sapiens kinesin heavy chain homolog mRNA, partial cds.
Other Names for This Gene
Alternate Gene Symbols: AB011103, DKFZp566O183 , Q9UFW7, Q9UFW7_HUMAN, uc320dmy.1UCSC ID: ENST00000435030.1RefSeq Accession: NM_004522.3 Protein: Q9UFW7
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
