Human Gene RESF1 (ENST00000312561.9_5) from GENCODE V47lift37
  Description: retroelement silencing factor 1 (from RefSeq NM_018169.4)
Gencode Transcript: ENST00000312561.9_5
Gencode Gene: ENSG00000174718.12_16
Transcript (Including UTRs)
   Position: hg19 chr12:32,112,349-32,146,041 Size: 33,693 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr12:32,133,890-32,145,469 Size: 11,580 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:32,112,349-32,146,041)mRNA (may differ from genome)Protein (1747 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: K1551_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein KIAA1551;
SEQUENCE CAUTION: Sequence=BAA91330.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=BAA91734.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB13377.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 30.83 RPKM in Ovary
Total median expression: 364.49 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -99.40418-0.238 Picture PostScript Text
3' UTR -109.50572-0.191 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15395 - Domain of unknown function (DUF4617)

ModBase Predicted Comparative 3D Structure on Q9HCM1
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  LF384207 - JP 2014500723-A/191710: Polycomb-Associated Non-Coding RNAs.
AK092399 - Homo sapiens cDNA FLJ35080 fis, clone PLACE6005294.
AX747522 - Sequence 1047 from Patent EP1308459.
BC140819 - Homo sapiens chromosome 12 open reading frame 35, mRNA (cDNA clone MGC:176496 IMAGE:9021687), complete cds.
MA619784 - JP 2018138019-A/191710: Polycomb-Associated Non-Coding RNAs.
LF366539 - JP 2014500723-A/174042: Polycomb-Associated Non-Coding RNAs.
KJ899094 - Synthetic construct Homo sapiens clone ccsbBroadEn_08488 C12orf35 gene, encodes complete protein.
LF366540 - JP 2014500723-A/174043: Polycomb-Associated Non-Coding RNAs.
LF366541 - JP 2014500723-A/174044: Polycomb-Associated Non-Coding RNAs.
AB046771 - Homo sapiens mRNA for KIAA1551 protein, partial cds.
LF366542 - JP 2014500723-A/174045: Polycomb-Associated Non-Coding RNAs.
AK000703 - Homo sapiens cDNA FLJ20696 fis, clone KAIA2488.
LF366543 - JP 2014500723-A/174046: Polycomb-Associated Non-Coding RNAs.
AK000688 - Homo sapiens cDNA FLJ20681 fis, clone KAIA4078.
LF366544 - JP 2014500723-A/174047: Polycomb-Associated Non-Coding RNAs.
LF366545 - JP 2014500723-A/174048: Polycomb-Associated Non-Coding RNAs.
LF366547 - JP 2014500723-A/174050: Polycomb-Associated Non-Coding RNAs.
LF366548 - JP 2014500723-A/174051: Polycomb-Associated Non-Coding RNAs.
AK001514 - Homo sapiens cDNA FLJ10652 fis, clone NT2RP2005886.
BC098115 - Homo sapiens chromosome 12 open reading frame 35, mRNA (cDNA clone IMAGE:40024082), partial cds.
BC114509 - Homo sapiens chromosome 12 open reading frame 35, mRNA (cDNA clone IMAGE:40024087), partial cds.
BC114956 - Homo sapiens chromosome 12 open reading frame 35, mRNA (cDNA clone IMAGE:40024088), partial cds.
LF366549 - JP 2014500723-A/174052: Polycomb-Associated Non-Coding RNAs.
LF366550 - JP 2014500723-A/174053: Polycomb-Associated Non-Coding RNAs.
LF366551 - JP 2014500723-A/174054: Polycomb-Associated Non-Coding RNAs.
LF366552 - JP 2014500723-A/174055: Polycomb-Associated Non-Coding RNAs.
LF366553 - JP 2014500723-A/174056: Polycomb-Associated Non-Coding RNAs.
LF366556 - JP 2014500723-A/174059: Polycomb-Associated Non-Coding RNAs.
JD101733 - Sequence 82757 from Patent EP1572962.
LF366557 - JP 2014500723-A/174060: Polycomb-Associated Non-Coding RNAs.
MA602116 - JP 2018138019-A/174042: Polycomb-Associated Non-Coding RNAs.
MA602117 - JP 2018138019-A/174043: Polycomb-Associated Non-Coding RNAs.
MA602118 - JP 2018138019-A/174044: Polycomb-Associated Non-Coding RNAs.
MA602119 - JP 2018138019-A/174045: Polycomb-Associated Non-Coding RNAs.
MA602120 - JP 2018138019-A/174046: Polycomb-Associated Non-Coding RNAs.
MA602121 - JP 2018138019-A/174047: Polycomb-Associated Non-Coding RNAs.
MA602122 - JP 2018138019-A/174048: Polycomb-Associated Non-Coding RNAs.
MA602124 - JP 2018138019-A/174050: Polycomb-Associated Non-Coding RNAs.
MA602125 - JP 2018138019-A/174051: Polycomb-Associated Non-Coding RNAs.
MA602126 - JP 2018138019-A/174052: Polycomb-Associated Non-Coding RNAs.
MA602127 - JP 2018138019-A/174053: Polycomb-Associated Non-Coding RNAs.
MA602128 - JP 2018138019-A/174054: Polycomb-Associated Non-Coding RNAs.
MA602129 - JP 2018138019-A/174055: Polycomb-Associated Non-Coding RNAs.
MA602130 - JP 2018138019-A/174056: Polycomb-Associated Non-Coding RNAs.
MA602133 - JP 2018138019-A/174059: Polycomb-Associated Non-Coding RNAs.
MA602134 - JP 2018138019-A/174060: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B2RTU5, C12orf35, ENST00000312561.1, ENST00000312561.2, ENST00000312561.3, ENST00000312561.4, ENST00000312561.5, ENST00000312561.6, ENST00000312561.7, ENST00000312561.8, KIAA1551, NM_018169, Q4KN17, Q9HCM1, Q9NVL6, Q9NWP9, RESF1 , RESF1_HUMAN, uc317pgf.1, uc317pgf.2
UCSC ID: ENST00000312561.9_5
RefSeq Accession: NM_018169.4
Protein: Q9HCM1 (aka K1551_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.