The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P17535
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0003677 DNA binding GO:0003690 double-stranded DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0003713 transcription coactivator activity GO:0005515 protein binding GO:0008134 transcription factor binding GO:0016922 ligand-dependent nuclear receptor binding GO:0019899 enzyme binding GO:0043565 sequence-specific DNA binding GO:0044212 transcription regulatory region DNA binding
Biological Process: GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO:0002076 osteoblast development GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006366 transcription from RNA polymerase II promoter GO:0007568 aging GO:0007623 circadian rhythm GO:0009314 response to radiation GO:0009416 response to light stimulus GO:0009612 response to mechanical stimulus GO:0010941 regulation of cell death GO:0014070 response to organic cyclic compound GO:0032496 response to lipopolysaccharide GO:0032870 cellular response to hormone stimulus GO:0034097 response to cytokine GO:0042127 regulation of cell proliferation GO:0042493 response to drug GO:0043434 response to peptide hormone GO:0045597 positive regulation of cell differentiation GO:0045669 positive regulation of osteoblast differentiation GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0051591 response to cAMP GO:0051726 regulation of cell cycle GO:0071277 cellular response to calcium ion
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
