ID:G3BP2_HUMAN DESCRIPTION: RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2; FUNCTION: Probable scaffold protein that may be involved in mRNA transport (Potential). SUBUNIT: Binds to the N-terminal domain of I-kappa-B-alpha. SUBCELLULAR LOCATION: Cytoplasm. PTM: Arg-457 and Arg-468 are dimethylated, probably to asymmetric dimethylarginine. SIMILARITY: Contains 1 NTF2 domain. SIMILARITY: Contains 1 RRM (RNA recognition motif) domain. SEQUENCE CAUTION: Sequence=BAA31635.2; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UN86
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007253 cytoplasmic sequestering of NF-kappaB GO:0007265 Ras protein signal transduction GO:0034063 stress granule assembly GO:0051028 mRNA transport
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
