Human Gene FAM117A (ENST00000240364.7_8) from GENCODE V47lift37

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Description: family with sequence similarity 117 member A (from RefSeq NM_030802.4)
Gencode Transcript: ENST00000240364.7_8
Gencode Gene: ENSG00000121104.8_14
Transcript (Including UTRs)
Position: hg19 chr17:47,787,694-47,841,493 Size: 53,800 Total Exon Count: 8 Strand: -
Coding Region
Position: hg19 chr17:47,788,617-47,841,449 Size: 52,833 Coding Exon Count: 8

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species	mRNA Descriptions
Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr17:47,787,694-47,841,493)			mRNA (may differ from genome)		Protein (453 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	MGI	PubMed	UniProtKB	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: F117A_HUMAN DESCRIPTION: RecName: Full=Protein FAM117A; AltName: Full=C/EBP-induced protein; SIMILARITY: Belongs to the FAM117 family.

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D016604 Aflatoxin B1 D000535 Aluminum D001564 Benzo(a)pyrene D019327 Copper Sulfate D016572 Cyclosporine D003993 Dibutyl Phthalate D005839 Gentamicins D006861 Hydrogen Peroxide D008942 Mitoxantrone D010100 Oxygen more ... click here to view the complete list

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 21.78 RPKM in Spleen Total median expression: 384.61 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-13.00	44	-0.295	Picture	PostScript	Text
3' UTR	-286.70	923	-0.311	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR026640 - FAM117A
IPR026642 - Glcci1/FAM117

Pfam Domains:
PF15388 - Protein Family FAM117

ModBase Predicted Comparative 3D Structure on Q9C073


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD	Ensembl

Descriptions from all associated GenBank mRNAs


	BC037572 - Homo sapiens family with sequence similarity 117, member A, mRNA (cDNA clone MGC:44930 IMAGE:5526752), complete cds. AF123073 - Homo sapiens C/EBP-induced protein mRNA, complete cds. BC065199 - Homo sapiens family with sequence similarity 117, member A, mRNA (cDNA clone MGC:70672 IMAGE:5214423), complete cds. AK302376 - Homo sapiens cDNA FLJ57293 complete cds, highly similar to Homo sapiens C/EBP-induced protein, mRNA. KJ905558 - Synthetic construct Homo sapiens clone ccsbBroadEn_15174 FAM117A gene, encodes complete protein. LF209272 - JP 2014500723-A/16775: Polycomb-Associated Non-Coding RNAs. MA444849 - JP 2018138019-A/16775: Polycomb-Associated Non-Coding RNAs. JD331167 - Sequence 312191 from Patent EP1572962. JD139491 - Sequence 120515 from Patent EP1572962. JD522668 - Sequence 503692 from Patent EP1572962. JD207736 - Sequence 188760 from Patent EP1572962. JD362744 - Sequence 343768 from Patent EP1572962. JD501378 - Sequence 482402 from Patent EP1572962. JD287945 - Sequence 268969 from Patent EP1572962. JD025678 - Sequence 6702 from Patent EP1572962. JD028423 - Sequence 9447 from Patent EP1572962. JD375144 - Sequence 356168 from Patent EP1572962. JD115928 - Sequence 96952 from Patent EP1572962. JD143886 - Sequence 124910 from Patent EP1572962. JD253631 - Sequence 234655 from Patent EP1572962. JD544484 - Sequence 525508 from Patent EP1572962. JD487608 - Sequence 468632 from Patent EP1572962. JD392742 - Sequence 373766 from Patent EP1572962. JD252077 - Sequence 233101 from Patent EP1572962. JD488389 - Sequence 469413 from Patent EP1572962. JD485082 - Sequence 466106 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: B7Z7Q3, ENST00000240364.1, ENST00000240364.2, ENST00000240364.3, ENST00000240364.4, ENST00000240364.5, ENST00000240364.6, F117A_HUMAN, NM_030802, Q9C073, uc317ehj.1, uc317ehj.2 UCSC ID: ENST00000240364.7_8 RefSeq Accession: NM_030802.4 Protein: Q9C073 (aka F117A_HUMAN)

Gene Model Information


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Methods, Credits, and Use Restrictions


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