ID:EXOC4_HUMAN DESCRIPTION: RecName: Full=Exocyst complex component 4; AltName: Full=Exocyst complex component Sec8; FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (By similarity). SUBUNIT: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with BIRC6/bruce. Interacts with MYRIP (By similarity). INTERACTION: Q9NR09:BIRC6; NbExp=3; IntAct=EBI-355383, EBI-1765160; SIMILARITY: Belongs to the SEC8 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF04048 - Sec8 exocyst complex component specific domain
SCOP Domains: 47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 52540 - P-loop containing nucleoside triphosphate hydrolases
ModBase Predicted Comparative 3D Structure on Q96A65
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
