ID:CASP_HUMAN DESCRIPTION: RecName: Full=Protein CASP; FUNCTION: May be involved in intra-Golgi retrograde transport. SUBUNIT: Homodimer; disulfide-linked. Interacts with GOLGA5. SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type IV membrane protein. SIMILARITY: Belongs to the CASP family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q13948
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK125076 - Homo sapiens cDNA FLJ43086 fis, clone BRTHA3019048, highly similar to Protein CASP. AK303151 - Homo sapiens cDNA FLJ57247 complete cds, highly similar to Protein CASP. AK222832 - Homo sapiens mRNA for CCAAT displacement protein isoform b variant, clone: HEP07381. AK125097 - Homo sapiens cDNA FLJ43107 fis, clone CTONG2020108, highly similar to Protein CASP. BC066592 - Homo sapiens cut-like homeobox 1, mRNA (cDNA clone MGC:75164 IMAGE:5740343), complete cds. L12579 - Human alternatively spliced CUTL1 mRNA, complete cds. AK297548 - Homo sapiens cDNA FLJ57747 complete cds, highly similar to Protein CASP. BC012323 - Homo sapiens cDNA clone IMAGE:4550607, containing frame-shift errors. AK122726 - Homo sapiens cDNA FLJ16230 fis, clone FEBRA2025249, highly similar to Protein CASP. BC025422 - Homo sapiens cut-like homeobox 1, mRNA (cDNA clone IMAGE:4864729), complete cds. AB462994 - Synthetic construct DNA, clone: pF1KB9775, Homo sapiens CUTL1 gene for cut-like homeobox 1, without stop codon, in Flexi system. M74099 - Human displacement protein (CCAAT) mRNA. AB075522 - Homo sapiens neuroblastoma cDNA, clone:Nbla10317, full insert sequence. KF421948 - Homo sapiens CUX1/RET fusion (CUX1/RET fusion) mRNA, partial cds. BC036852 - Homo sapiens mRNA similar to cut-like 1, CCAAT displacement protein (Drosophila) (cDNA clone IMAGE:5415882). JD123985 - Sequence 105009 from Patent EP1572962. JD226573 - Sequence 207597 from Patent EP1572962. JD442338 - Sequence 423362 from Patent EP1572962. JD335725 - Sequence 316749 from Patent EP1572962. JD392070 - Sequence 373094 from Patent EP1572962. JD465448 - Sequence 446472 from Patent EP1572962. JD367823 - Sequence 348847 from Patent EP1572962. JD067690 - Sequence 48714 from Patent EP1572962. JD397594 - Sequence 378618 from Patent EP1572962. JD123637 - Sequence 104661 from Patent EP1572962. JD387326 - Sequence 368350 from Patent EP1572962. JD382235 - Sequence 363259 from Patent EP1572962. JD112797 - Sequence 93821 from Patent EP1572962. JD228488 - Sequence 209512 from Patent EP1572962. JD209277 - Sequence 190301 from Patent EP1572962. JD275191 - Sequence 256215 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q13948 (Reactome details) participates in the following event(s):
R-HSA-8847544 The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering R-HSA-6811438 Intra-Golgi traffic R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
