ID:COX17_HUMAN DESCRIPTION: RecName: Full=Cytochrome c oxidase copper chaperone; FUNCTION: Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity). SUBUNIT: Interacts with COA1. SUBCELLULAR LOCATION: Mitochondrion intermembrane space (By similarity). TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to the COX17 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q14061
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006091 generation of precursor metabolites and energy GO:0006825 copper ion transport GO:0007420 brain development GO:0007507 heart development GO:0008284 positive regulation of cell proliferation GO:0033617 mitochondrial respiratory chain complex IV assembly GO:1904960 positive regulation of cytochrome-c oxidase activity
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
