Human Gene CEP44 (ENST00000503780.6_9) from GENCODE V47lift37

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Description: centrosomal protein 44, transcript variant 1 (from RefSeq NM_001040157.3)
Gencode Transcript: ENST00000503780.6_9
Gencode Gene: ENSG00000164118.13_16
Transcript (Including UTRs)
Position: hg19 chr4:175,205,062-175,241,479 Size: 36,418 Total Exon Count: 12 Strand: +
Coding Region
Position: hg19 chr4:175,220,273-175,238,534 Size: 18,262 Coding Exon Count: 10

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species	GO Annotations
mRNA Descriptions	Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr4:175,205,062-175,241,479)			mRNA (may differ from genome)		Protein (390 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	MGI	PubMed	UniProtKB	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: CEP44_HUMAN DESCRIPTION: RecName: Full=Centrosomal protein of 44 kDa; AltName: Full=HBV PreS1-transactivated protein 3; Short=PS1TP3; SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Localizes to centrosomes, spindle poles, and weakly in midbody. SEQUENCE CAUTION: Sequence=BAB21803.1; Type=Erroneous initiation;

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000393 Air Pollutants D001564 Benzo(a)pyrene D003993 Dibutyl Phthalate C028473 N-acetyl-4-benzoquinoneimine D010634 Phenobarbital C006780 bisphenol A

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 5.36 RPKM in Cells - EBV-transformed lymphocytes Total median expression: 159.45 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-46.50	180	-0.258	Picture	PostScript	Text
3' UTR	-716.40	2945	-0.243	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

Pfam Domains:
PF15007 - Centrosomal spindle body, CEP44

ModBase Predicted Comparative 3D Structure on Q9C0F1


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Gene Ontology (GO) Annotations with Structured Vocabulary


	Molecular Function: GO:0005515 protein binding Cellular Component: GO:0000922 spindle pole GO:0005737 cytoplasm GO:0005813 centrosome GO:0005815 microtubule organizing center GO:0005856 cytoskeleton GO:0030496 midbody

Descriptions from all associated GenBank mRNAs


	BC038667 - Homo sapiens KIAA1712, mRNA (cDNA clone MGC:33587 IMAGE:4823994), complete cds. AK292484 - Homo sapiens cDNA FLJ78628 complete cds. AK094961 - Homo sapiens cDNA FLJ37642 fis, clone BRHIP2000163. KJ904892 - Synthetic construct Homo sapiens clone ccsbBroadEn_14286 CEP44 gene, encodes complete protein. JD064781 - Sequence 45805 from Patent EP1572962. JD415582 - Sequence 396606 from Patent EP1572962. AB051499 - Homo sapiens KIAA1712 mRNA for KIAA1712 protein. JD305766 - Sequence 286790 from Patent EP1572962. AB384268 - Synthetic construct DNA, clone: pF1KSDA1712, Homo sapiens KIAA1712 gene for KIAA1712 protein, complete cds, without stop codon, in Flexi system. AY426674 - Homo sapiens HBV PreS1-transactivated protein 3 mRNA, complete cds. JD073311 - Sequence 54335 from Patent EP1572962. JD112921 - Sequence 93945 from Patent EP1572962. JD357103 - Sequence 338127 from Patent EP1572962. JD485434 - Sequence 466458 from Patent EP1572962. JD482338 - Sequence 463362 from Patent EP1572962. JD300697 - Sequence 281721 from Patent EP1572962. JD292083 - Sequence 273107 from Patent EP1572962. JD181570 - Sequence 162594 from Patent EP1572962. JD523715 - Sequence 504739 from Patent EP1572962. JD523714 - Sequence 504738 from Patent EP1572962. JD467608 - Sequence 448632 from Patent EP1572962. JD428587 - Sequence 409611 from Patent EP1572962. JD550731 - Sequence 531755 from Patent EP1572962. JD562140 - Sequence 543164 from Patent EP1572962. JD293309 - Sequence 274333 from Patent EP1572962. JD087024 - Sequence 68048 from Patent EP1572962. JD262025 - Sequence 243049 from Patent EP1572962. JD432400 - Sequence 413424 from Patent EP1572962. JD560905 - Sequence 541929 from Patent EP1572962. JD542644 - Sequence 523668 from Patent EP1572962. JD212574 - Sequence 193598 from Patent EP1572962. JD553426 - Sequence 534450 from Patent EP1572962. JD244455 - Sequence 225479 from Patent EP1572962. JD091427 - Sequence 72451 from Patent EP1572962. JD549557 - Sequence 530581 from Patent EP1572962. JD263385 - Sequence 244409 from Patent EP1572962. JD413613 - Sequence 394637 from Patent EP1572962. JD367075 - Sequence 348099 from Patent EP1572962. JD325560 - Sequence 306584 from Patent EP1572962. JD418044 - Sequence 399068 from Patent EP1572962. JD147301 - Sequence 128325 from Patent EP1572962. JD293349 - Sequence 274373 from Patent EP1572962. JD457468 - Sequence 438492 from Patent EP1572962. JD388882 - Sequence 369906 from Patent EP1572962. JD353084 - Sequence 334108 from Patent EP1572962. JD353085 - Sequence 334109 from Patent EP1572962. JD258819 - Sequence 239843 from Patent EP1572962. JD152340 - Sequence 133364 from Patent EP1572962. JD256843 - Sequence 237867 from Patent EP1572962. JD407664 - Sequence 388688 from Patent EP1572962. JD139292 - Sequence 120316 from Patent EP1572962. JD461009 - Sequence 442033 from Patent EP1572962. JD119886 - Sequence 100910 from Patent EP1572962. JD385127 - Sequence 366151 from Patent EP1572962. JD417313 - Sequence 398337 from Patent EP1572962. JD333638 - Sequence 314662 from Patent EP1572962. JD251652 - Sequence 232676 from Patent EP1572962. BC045590 - Homo sapiens cDNA clone IMAGE:5276927. JD114097 - Sequence 95121 from Patent EP1572962. JD187904 - Sequence 168928 from Patent EP1572962. JD384936 - Sequence 365960 from Patent EP1572962. JD042346 - Sequence 23370 from Patent EP1572962. JD313141 - Sequence 294165 from Patent EP1572962. JD304736 - Sequence 285760 from Patent EP1572962. JD047077 - Sequence 28101 from Patent EP1572962. JD067117 - Sequence 48141 from Patent EP1572962. JD558175 - Sequence 539199 from Patent EP1572962. JD221306 - Sequence 202330 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A8K8W9, A8MW11, B3KT53, CEP44_HUMAN, D3DP42, ENST00000503780.1, ENST00000503780.2, ENST00000503780.3, ENST00000503780.4, ENST00000503780.5, KIAA1712, NM_001040157, Q8IXZ4, Q9C0F1, uc322xqg.1, uc322xqg.2 UCSC ID: ENST00000503780.6_9 RefSeq Accession: NM_001040157.3 Protein: Q9C0F1 (aka CEP44_HUMAN)

Gene Model Information


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Methods, Credits, and Use Restrictions


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