ID:CADH9_HUMAN DESCRIPTION: RecName: Full=Cadherin-9; Flags: Precursor; FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (Potential). SIMILARITY: Contains 5 cadherin domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9ULB4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Cellular Component: GO:0005886 plasma membrane GO:0016020 membrane GO:0016021 integral component of membrane GO:0099055 integral component of postsynaptic membrane GO:0099056 integral component of presynaptic membrane
Descriptions from all associated GenBank mRNAs
AB035302 - Homo sapiens CDH9 mRNA for cadherin-9, complete cds. BC107594 - Homo sapiens cadherin 9, type 2 (T1-cadherin), mRNA (cDNA clone MGC:125387 IMAGE:40011942), complete cds. BC113745 - Homo sapiens cadherin 9, type 2 (T1-cadherin), mRNA (cDNA clone MGC:125386 IMAGE:40011941), complete cds. AK307779 - Homo sapiens cDNA, FLJ97727. AK308697 - Homo sapiens cDNA, FLJ98738. BC109384 - Homo sapiens cadherin 9, type 2 (T1-cadherin), mRNA (cDNA clone IMAGE:40011943), partial cds. AK294183 - Homo sapiens cDNA FLJ57804 complete cds, highly similar to Cadherin-9 precursor. KJ896581 - Synthetic construct Homo sapiens clone ccsbBroadEn_05975 CDH9 gene, encodes complete protein. JD059144 - Sequence 40168 from Patent EP1572962. JD049901 - Sequence 30925 from Patent EP1572962. JD501860 - Sequence 482884 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9ULB4 (Reactome details) participates in the following event(s):
R-HSA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin R-HSA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin R-HSA-418990 Adherens junctions interactions R-HSA-421270 Cell-cell junction organization R-HSA-446728 Cell junction organization R-HSA-1500931 Cell-Cell communication
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
