Human Gene CCDC77 (ENST00000239830.9_6) from GENCODE V47lift37
  Description: coiled-coil domain containing 77, transcript variant 1 (from RefSeq NM_032358.4)
Gencode Transcript: ENST00000239830.9_6
Gencode Gene: ENSG00000120647.10_19
Transcript (Including UTRs)
   Position: hg19 chr12:510,810-551,808 Size: 40,999 Total Exon Count: 13 Strand: +
Coding Region
   Position: hg19 chr12:518,550-551,086 Size: 32,537 Coding Exon Count: 11 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:510,810-551,808)mRNA (may differ from genome)Protein (488 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CCD77_HUMAN
DESCRIPTION: RecName: Full=Coiled-coil domain-containing protein 77;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.84 RPKM in Testis
Total median expression: 132.65 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -27.00111-0.243 Picture PostScript Text
3' UTR -196.60722-0.272 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9BR77
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005813 centrosome
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  AK316029 - Homo sapiens cDNA, FLJ78928 complete cds.
AK308216 - Homo sapiens cDNA, FLJ98164.
LF384183 - JP 2014500723-A/191686: Polycomb-Associated Non-Coding RNAs.
AK293165 - Homo sapiens cDNA FLJ58763 complete cds.
AK027638 - Homo sapiens cDNA FLJ14732 fis, clone NT2RP3001969, weakly similar to TRICHOHYALIN.
BC006444 - Homo sapiens coiled-coil domain containing 77, mRNA (cDNA clone MGC:13183 IMAGE:3616619), complete cds.
MA619760 - JP 2018138019-A/191686: Polycomb-Associated Non-Coding RNAs.
LF365597 - JP 2014500723-A/173100: Polycomb-Associated Non-Coding RNAs.
LF365595 - JP 2014500723-A/173098: Polycomb-Associated Non-Coding RNAs.
LF365594 - JP 2014500723-A/173097: Polycomb-Associated Non-Coding RNAs.
MA601174 - JP 2018138019-A/173100: Polycomb-Associated Non-Coding RNAs.
MA601172 - JP 2018138019-A/173098: Polycomb-Associated Non-Coding RNAs.
MA601171 - JP 2018138019-A/173097: Polycomb-Associated Non-Coding RNAs.
LF365593 - JP 2014500723-A/173096: Polycomb-Associated Non-Coding RNAs.
LF365590 - JP 2014500723-A/173093: Polycomb-Associated Non-Coding RNAs.
LF365588 - JP 2014500723-A/173091: Polycomb-Associated Non-Coding RNAs.
LF365585 - JP 2014500723-A/173088: Polycomb-Associated Non-Coding RNAs.
LF365584 - JP 2014500723-A/173087: Polycomb-Associated Non-Coding RNAs.
LF365582 - JP 2014500723-A/173085: Polycomb-Associated Non-Coding RNAs.
LF365581 - JP 2014500723-A/173084: Polycomb-Associated Non-Coding RNAs.
JD353580 - Sequence 334604 from Patent EP1572962.
JD038756 - Sequence 19780 from Patent EP1572962.
JD345806 - Sequence 326830 from Patent EP1572962.
JD453986 - Sequence 435010 from Patent EP1572962.
JD512958 - Sequence 493982 from Patent EP1572962.
JD204522 - Sequence 185546 from Patent EP1572962.
JD473374 - Sequence 454398 from Patent EP1572962.
MA601170 - JP 2018138019-A/173096: Polycomb-Associated Non-Coding RNAs.
MA601167 - JP 2018138019-A/173093: Polycomb-Associated Non-Coding RNAs.
MA601165 - JP 2018138019-A/173091: Polycomb-Associated Non-Coding RNAs.
MA601162 - JP 2018138019-A/173088: Polycomb-Associated Non-Coding RNAs.
MA601161 - JP 2018138019-A/173087: Polycomb-Associated Non-Coding RNAs.
MA601159 - JP 2018138019-A/173085: Polycomb-Associated Non-Coding RNAs.
MA601158 - JP 2018138019-A/173084: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B4DDE8, CCD77_HUMAN, ENST00000239830.1, ENST00000239830.2, ENST00000239830.3, ENST00000239830.4, ENST00000239830.5, ENST00000239830.6, ENST00000239830.7, ENST00000239830.8, NM_032358, Q9BR77, uc317egb.1, uc317egb.2
UCSC ID: ENST00000239830.9_6
RefSeq Accession: NM_032358.4
Protein: Q9BR77 (aka CCD77_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.