Human Gene CASP12 (ENST00000613512.4_9) from GENCODE V47lift37
  Description: caspase 12 (gene/pseudogene) (from HGNC CASP12)
Gencode Transcript: ENST00000613512.4_9
Gencode Gene: ENSG00000204403.11_17
Transcript (Including UTRs)
   Position: hg19 chr11:104,756,445-104,769,160 Size: 12,716 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg19 chr11:104,757,441-104,769,141 Size: 11,701 Coding Exon Count: 7 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:104,756,445-104,769,160)mRNA (may differ from genome)Protein (341 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsHGNC
MalacardsMGIOMIMPubMedWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: CASP12
Diseases sorted by gene-association score: alzheimer disease mitochondrial (7)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -1.2019-0.063 Picture PostScript Text
3' UTR -53.50406-0.132 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  AX721173 - Sequence 133 from Patent WO0220754.
AY358222 - Homo sapiens clone DNA209852 CASP12P1 (UNQ9415) mRNA, complete cds.
AF464191 - Homo sapiens caspase 12 variant gamma (CASP12) pseudogene mRNA, complete sequence; alternatively spliced.
AF464192 - Homo sapiens caspase 12 variant epsilon (CASP12) mRNA, complete sequence; alternatively spliced.
AF464193 - Homo sapiens caspase 12 variant delta (CASP12) mRNA, complete sequence; alternatively spliced.
AF464194 - Homo sapiens caspase 12 variant eta (CASP12) mRNA, complete sequence; alternatively spliced.
AF464195 - Homo sapiens caspase 12 variant iota (CASP12) mRNA, complete sequence; alternatively spliced.
AF486844 - Homo sapiens caspase 12 variant alpha (CASP12) mRNA, complete sequence; alternatively spliced.
AF486845 - Homo sapiens caspase 12 variant beta (CASP12) mRNA, complete sequence; alternatively spliced.
AF486846 - Homo sapiens caspase 12 variant zeta (CASP12) mRNA, complete sequence; alternatively spliced.
AF486847 - Homo sapiens caspase 12 variant theta (CASP12) mRNA, complete sequence; alternatively spliced.
HV708960 - JP 2012506450-A/58: Methods for treating eye disorders.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000613512.1, ENST00000613512.2, ENST00000613512.3, NR_034061, uc327oqy.1, uc327oqy.2
UCSC ID: ENST00000613512.4_9
Representative RNA: NR_034061

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.