ID:BTF3_HUMAN DESCRIPTION: RecName: Full=Transcription factor BTF3; AltName: Full=RNA polymerase B transcription factor 3; FUNCTION: General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription. INTERACTION: P03372:ESR1; NbExp=5; IntAct=EBI-1054703, EBI-78473; SUBCELLULAR LOCATION: Nucleus. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: Belongs to the NAC-beta family. SIMILARITY: Contains 1 NAC-A/B (NAC-alpha/beta) domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P20290
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0001701 in utero embryonic development GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006366 transcription from RNA polymerase II promoter GO:0015031 protein transport
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
