Human Gene B3GNT9 (ENST00000449549.4_7) from GENCODE V47lift37
  Description: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 (from RefSeq NM_033309.3)
Gencode Transcript: ENST00000449549.4_7
Gencode Gene: ENSG00000237172.4_9
Transcript (Including UTRs)
   Position: hg19 chr16:67,182,007-67,184,901 Size: 2,895 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr16:67,183,180-67,184,388 Size: 1,209 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:67,182,007-67,184,901)mRNA (may differ from genome)Protein (402 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedReactomeUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: B3GN9_HUMAN
DESCRIPTION: RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9; Short=BGnT-9; Short=Beta-1,3-Gn-T9; Short=Beta-1,3-N-acetylglucosaminyltransferase 9; Short=Beta3Gn-T9; EC=2.4.1.-;
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein (Potential).
SIMILARITY: Belongs to the glycosyltransferase 31 family.
SEQUENCE CAUTION: Sequence=BC012191; Type=Frameshift; Positions=81;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 2.89 RPKM in Artery - Aorta
Total median expression: 51.42 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -185.50320-0.580 Picture PostScript Text
3' UTR -388.901173-0.332 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002659 - Glyco_trans_31

Pfam Domains:
PF01762 - Galactosyltransferase
PF02434 - Fringe-like

ModBase Predicted Comparative 3D Structure on Q6UX72
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0008378 galactosyltransferase activity
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups

Biological Process:
GO:0006486 protein glycosylation

Cellular Component:
GO:0000139 Golgi membrane
GO:0001650 fibrillar center
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC012191 - Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, mRNA (cDNA clone IMAGE:4550086), containing frame-shift errors.
AF171091 - Homo sapiens MSTP082 (MST082) mRNA, complete cds.
BC022849 - Homo sapiens hypothetical protein MGC4655, mRNA (cDNA clone IMAGE:4039981), partial cds.
AY358485 - Homo sapiens clone DNA83505 galactosyltransferase (UNQ1922) mRNA, complete cds.
JD449890 - Sequence 430914 from Patent EP1572962.
JD166606 - Sequence 147630 from Patent EP1572962.
JD453008 - Sequence 434032 from Patent EP1572962.
JD067599 - Sequence 48623 from Patent EP1572962.
LF212227 - JP 2014500723-A/19730: Polycomb-Associated Non-Coding RNAs.
JD151182 - Sequence 132206 from Patent EP1572962.
JD163497 - Sequence 144521 from Patent EP1572962.
JD511209 - Sequence 492233 from Patent EP1572962.
JD462231 - Sequence 443255 from Patent EP1572962.
JD318526 - Sequence 299550 from Patent EP1572962.
JD557158 - Sequence 538182 from Patent EP1572962.
KJ905578 - Synthetic construct Homo sapiens clone ccsbBroadEn_15199 B3GNT9-like gene, encodes complete protein.
DQ590147 - Homo sapiens piRNA piR-57259, complete sequence.
JD022073 - Sequence 3097 from Patent EP1572962.
JD027896 - Sequence 8920 from Patent EP1572962.
JD076784 - Sequence 57808 from Patent EP1572962.
JD479047 - Sequence 460071 from Patent EP1572962.
JD230754 - Sequence 211778 from Patent EP1572962.
MA447804 - JP 2018138019-A/19730: Polycomb-Associated Non-Coding RNAs.

-  Biochemical and Signaling Pathways
  Reactome (by CSHL, EBI, and GO)

Protein Q6UX72 (Reactome details) participates in the following event(s):

R-HSA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein
R-HSA-913709 O-linked glycosylation of mucins
R-HSA-5173105 O-linked glycosylation
R-HSA-597592 Post-translational protein modification
R-HSA-392499 Metabolism of proteins

-  Other Names for This Gene
  Alternate Gene Symbols: B3GN9_HUMAN, B3GNT9 , ENST00000449549.1, ENST00000449549.2, ENST00000449549.3, NM_033309, Q6UX72, Q96EK0, uc320raw.1, uc320raw.2, UNQ1922/PRO4397
UCSC ID: ENST00000449549.4_7
RefSeq Accession: NM_033309.3
Protein: Q6UX72 (aka B3GN9_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.