Human Gene ARPP21 (ENST00000684406.1_6) from GENCODE V47lift37
  Description: cAMP regulated phosphoprotein 21, transcript variant 59 (from RefSeq NR_170707.1)
Gencode Transcript: ENST00000684406.1_6
Gencode Gene: ENSG00000172995.17_17
Transcript (Including UTRs)
   Position: hg19 chr3:35,681,017-35,835,978 Size: 154,962 Total Exon Count: 21 Strand: +
Coding Region
   Position: hg19 chr3:35,723,244-35,835,450 Size: 112,207 Coding Exon Count: 19 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:35,681,017-35,835,978)mRNA (may differ from genome)Protein (847 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MalacardsMGIPubMedUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ARPP21
Diseases sorted by gene-association score: shoulder impingement syndrome (2), calcific tendinitis (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -350.401086-0.323 Picture PostScript Text
3' UTR -120.00528-0.227 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  BC036399 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone MGC:43232 IMAGE:5263894), complete cds.
BC051828 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone MGC:60100 IMAGE:6012704), complete cds.
AK294484 - Homo sapiens cDNA FLJ61232 complete cds, highly similar to Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD (ARPP-21), transcript variant 1, mRNA.
KJ905402 - Synthetic construct Homo sapiens clone ccsbBroadEn_14976 ARPP21 gene, encodes complete protein.
AL133109 - Homo sapiens mRNA; cDNA DKFZp566N1047 (from clone DKFZp566N1047).
BC031106 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:5275494), complete cds.
BC041385 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:5276062), complete cds.
AK057559 - Homo sapiens cDNA FLJ32997 fis, clone THYMU1000144.
AK055064 - Homo sapiens cDNA FLJ30502 fis, clone BRAWH2000482, highly similar to cAMP-regulated phosphoprotein 21.
AK289868 - Homo sapiens cDNA FLJ78374 complete cds.
AF112220 - Homo sapiens cyclic AMP-regulated phosphoprotein mRNA, complete cds.
AK289649 - Homo sapiens cDNA FLJ78233 complete cds.
BC017805 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:4687451), complete cds.
BC066651 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:6044415), complete cds.
BC036548 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:5263838), with apparent retained intron.
HQ447775 - Synthetic construct Homo sapiens clone IMAGE:100071106; CCSB012887_03 cyclic AMP-regulated phosphoprotein, 21 kD (ARPP-21) gene, encodes complete protein.
EU831438 - Synthetic construct Homo sapiens clone HAIB:100066467; DKFZo008D0217 cyclic AMP-regulated phosphoprotein, 21 kD protein (ARPP-21) gene, encodes complete protein.
EU831530 - Synthetic construct Homo sapiens clone HAIB:100066559; DKFZo004D0218 cyclic AMP-regulated phosphoprotein, 21 kD protein (ARPP-21) gene, encodes complete protein.
BX537647 - Homo sapiens mRNA; cDNA DKFZp686B22204 (from clone DKFZp686B22204).
AK093648 - Homo sapiens cDNA FLJ36329 fis, clone THYMU2005855.
AX748241 - Sequence 1766 from Patent EP1308459.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A804HI65, A0A804HI65_HUMAN, ARPP21 , NR_170707, uc330mve.1, uc330mve.2
UCSC ID: ENST00000684406.1_6
RefSeq Accession: NM_001385562.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.