Human Gene ARPP21 (ENST00000684406.1_6) from GENCODE V47lift37

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Description: cAMP regulated phosphoprotein 21, transcript variant 59 (from RefSeq NR_170707.1)
Gencode Transcript: ENST00000684406.1_6
Gencode Gene: ENSG00000172995.17_17
Transcript (Including UTRs)
Position: hg19 chr3:35,681,017-35,835,978 Size: 154,962 Total Exon Count: 21 Strand: +
Coding Region
Position: hg19 chr3:35,723,244-35,835,450 Size: 112,207 Coding Exon Count: 19

Page Index	Sequence and Links	Primers	MalaCards	CTD	Gene Alleles
Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names	Model Information
Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr3:35,681,017-35,835,978)			mRNA (may differ from genome)		Protein (847 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	ExonPrimer	GeneCards	HGNC
Malacards	MGI	PubMed	UniProtKB	Wikipedia

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: ARPP21 Diseases sorted by gene-association score: shoulder impingement syndrome (2), calcific tendinitis (1)

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C006253 pirinixic acid C103505 AM 251 D001629 Bezafibrate D003042 Cocaine D004041 Dietary Fats D000431 Ethanol D019469 Indinavir D007657 Ketone Bodies D019259 Lamivudine D009020 Morphine more ... click here to view the complete list

Common Gene Haplotype Alleles


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Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-350.40	1086	-0.323	Picture	PostScript	Text
3' UTR	-120.00	528	-0.227	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Descriptions from all associated GenBank mRNAs


	BC036399 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone MGC:43232 IMAGE:5263894), complete cds. BC051828 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone MGC:60100 IMAGE:6012704), complete cds. AK294484 - Homo sapiens cDNA FLJ61232 complete cds, highly similar to Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD (ARPP-21), transcript variant 1, mRNA. KJ905402 - Synthetic construct Homo sapiens clone ccsbBroadEn_14976 ARPP21 gene, encodes complete protein. AL133109 - Homo sapiens mRNA; cDNA DKFZp566N1047 (from clone DKFZp566N1047). BC031106 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:5275494), complete cds. BC041385 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:5276062), complete cds. AK057559 - Homo sapiens cDNA FLJ32997 fis, clone THYMU1000144. AK055064 - Homo sapiens cDNA FLJ30502 fis, clone BRAWH2000482, highly similar to cAMP-regulated phosphoprotein 21. AK289868 - Homo sapiens cDNA FLJ78374 complete cds. AF112220 - Homo sapiens cyclic AMP-regulated phosphoprotein mRNA, complete cds. AK289649 - Homo sapiens cDNA FLJ78233 complete cds. BC017805 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:4687451), complete cds. BC066651 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:6044415), complete cds. BC036548 - Homo sapiens cyclic AMP-regulated phosphoprotein, 21 kD, mRNA (cDNA clone IMAGE:5263838), with apparent retained intron. HQ447775 - Synthetic construct Homo sapiens clone IMAGE:100071106; CCSB012887_03 cyclic AMP-regulated phosphoprotein, 21 kD (ARPP-21) gene, encodes complete protein. EU831438 - Synthetic construct Homo sapiens clone HAIB:100066467; DKFZo008D0217 cyclic AMP-regulated phosphoprotein, 21 kD protein (ARPP-21) gene, encodes complete protein. EU831530 - Synthetic construct Homo sapiens clone HAIB:100066559; DKFZo004D0218 cyclic AMP-regulated phosphoprotein, 21 kD protein (ARPP-21) gene, encodes complete protein. BX537647 - Homo sapiens mRNA; cDNA DKFZp686B22204 (from clone DKFZp686B22204). AK093648 - Homo sapiens cDNA FLJ36329 fis, clone THYMU2005855. AX748241 - Sequence 1766 from Patent EP1308459.

Other Names for This Gene


	Alternate Gene Symbols: A0A804HI65, A0A804HI65_HUMAN, ARPP21 , NR_170707, uc330mve.1, uc330mve.2 UCSC ID: ENST00000684406.1_6 RefSeq Accession: NM_001385562.1

Gene Model Information


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Methods, Credits, and Use Restrictions


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