Human Gene ADH7 (ENST00000437033.7_7) from GENCODE V47lift37
  Description: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide, transcript variant 2 (from RefSeq NM_000673.7)
Gencode Transcript: ENST00000437033.7_7
Gencode Gene: ENSG00000196344.12_9
Transcript (Including UTRs)
   Position: hg19 chr4:100,333,420-100,356,499 Size: 23,080 Total Exon Count: 9 Strand: -
Coding Region
   Position: hg19 chr4:100,334,305-100,356,390 Size: 22,086 Coding Exon Count: 9 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:100,333,420-100,356,499)mRNA (may differ from genome)Protein (374 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ADH7
Diseases sorted by gene-association score: atrophic gastritis (13), alcohol dependence (10), gastritis (7), fetal alcohol spectrum disorder (5), fetal alcohol syndrome (4)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • D013749 Tetrachlorodibenzodioxin
  • C076994 perfluorooctane sulfonic acid
  • C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene
  • C015802 2,6-dichloro-4-nitrophenol
  • C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester
  • D019840 2-Propanol
  • C018855 2-tert-butylhydroquinone
  • C023035 3,4,5,3',4'-pentachlorobiphenyl
  • C027576 4-hydroxy-2-nonenal
  • D000082 Acetaminophen
          more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 91.50 RPKM in Esophagus - Mucosa
Total median expression: 93.69 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -21.30109-0.195 Picture PostScript Text
3' UTR -157.60885-0.178 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  X76342 - H.sapiens ADH7 mRNA.
U09623 - Human alcohol dehydrogenase (ADH7) mRNA, complete cds.
JD410826 - Sequence 391850 from Patent EP1572962.
JD337261 - Sequence 318285 from Patent EP1572962.
JD565943 - Sequence 546967 from Patent EP1572962.
U07821 - Human alcohol dehydrogenase (ADH7) mRNA, complete cds.
JD284758 - Sequence 265782 from Patent EP1572962.
BC131512 - Homo sapiens alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide, mRNA (cDNA clone MGC:138874 IMAGE:40083994), complete cds.
JD158414 - Sequence 139438 from Patent EP1572962.
AK223472 - Homo sapiens mRNA, class IV alcohol dehydrogenase 7 mu or sigma subunit variant, clone: FCC118A08.
JD357894 - Sequence 338918 from Patent EP1572962.
JD288616 - Sequence 269640 from Patent EP1572962.
JD043054 - Sequence 24078 from Patent EP1572962.
JD524387 - Sequence 505411 from Patent EP1572962.
AK301696 - Homo sapiens cDNA FLJ51127 complete cds, highly similar to Alcohol dehydrogenase class 4 mu/sigma chain (EC 1.1.1.1).
JD089341 - Sequence 70365 from Patent EP1572962.
JD346969 - Sequence 327993 from Patent EP1572962.
AK301657 - Homo sapiens cDNA FLJ51125 complete cds, highly similar to Alcohol dehydrogenase class 4 mu/sigma chain (EC 1.1.1.1).
JD206816 - Sequence 187840 from Patent EP1572962.
L33179 - Human class IV sigma-1 alcohol dehydrogenase mRNA, complete cds.
AK312854 - Homo sapiens cDNA, FLJ93297, highly similar to Homo sapiens alcohol dehydrogenase 7 (class IV), mu or sigmapolypeptide (ADH7), mRNA.
KJ890635 - Synthetic construct Homo sapiens clone ccsbBroadEn_00029 ADH7 gene, encodes complete protein.
AK310811 - Homo sapiens cDNA, FLJ17853.
S77168 - ADH7=class IV alcohol dehydrogenase [human, stomach, mRNA Partial, 219 nt].
JD090286 - Sequence 71310 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0C4DG85, A0A0C4DG85_HUMAN, ADH7 , ENST00000437033.1, ENST00000437033.2, ENST00000437033.3, ENST00000437033.4, ENST00000437033.5, ENST00000437033.6, NM_000673, uc320fjp.1, uc320fjp.2
UCSC ID: ENST00000437033.7_7
RefSeq Accession: NM_000673.7

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.