The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6IRT1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0004022 alcohol dehydrogenase (NAD) activity GO:0008270 zinc ion binding GO:0016491 oxidoreductase activity GO:0042803 protein homodimerization activity GO:0046872 metal ion binding GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity
Biological Process: GO:0001523 retinoid metabolic process GO:0003016 respiratory system process GO:0006069 ethanol oxidation GO:0018119 peptidyl-cysteine S-nitrosylation GO:0032496 response to lipopolysaccharide GO:0045777 positive regulation of blood pressure GO:0046294 formaldehyde catabolic process GO:0051409 response to nitrosative stress GO:0055114 oxidation-reduction process